High-density EEG in Neurological Disorders

Healthy Clinical Trial

Official title:

High-density EEG in Neurological Disorders

Clinical Trial Details — Status: Enrolling by invitation

Administrative data

• NCT number: NCT04266041
• Other study ID #: D18111 30813
• Status: Enrolling by invitation
• Phase: N/A
• Start date: February 9, 2018
• Est. completion date: March 9, 2028

Study information

• Verified date: July 2023
• Source: Dartmouth-Hitchcock Medical Center
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of the study is to use a new method of high-density electroencephalogram (HD-EEG) recording to map brain areas important for movement, sensation, language, emotion, and cognition.

Description:

This study will measure brain waves using high-density EEG. Participants will be asked wear a cap with electrodes attached to it. During the recording, participants may be asked to rest, sleep, or complete a task. The tasks involve viewing pictures, answering questions, speaking, or moving an arm or leg. Recordings generally last between 60-120 minutes.*

Recruitment information / eligibility

• Status: Enrolling by invitation
• Enrollment: 100
• Est. completion date: March 9, 2028
• Est. primary completion date: February 9, 2028
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Able to perform the tasks
• Able to give own consent

Exclusion Criteria:

• Any neurologic or psychiatric diagnosis such as stroke, tumor, or psychosis judged to interfere with high-density EEG.

Related Conditions & MeSH terms

• Epilepsy
• Healthy
• Nervous System Diseases
• Tumor

Intervention

Diagnostic Test:
• High-density electroencephalogram (HD-EEG)
This study will focus on obtaining a special type of high-density scalp electroencephalography (HD-EEG) recordings in patients with neurological disorders (i.e., epilepsy, brain tumor, stroke, etc.) and appropriately matched controls. HD-EEG is a scalp EEG which uses up to 256 channels compared to the standard 21 channels used for routine clinical applications. The reason for using more channels to record is for more precise localization of epileptogenic foci and/or more precise mapping of brain functions. This type of EEG requires the use of patient's own MRI scan to precisely localize activity. Therefore, all patients and controls getting an HD-EEG will require a structural MRI scan.

Locations

Country	Name	City	State
United States	Dartmouth-Hitchcock Medical Center	Lebanon	New Hampshire

Sponsors (1)

Lead Sponsor	Collaborator
Dartmouth-Hitchcock Medical Center

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Localize brain functions in patients and healthy controls	Localize brain functions using high-density EEG recordings	60 - 90 minutes
Secondary	Localize brain areas involved in language	Localize brain areas involved in language using high-density EEG recordings	60 - 90 minutes
Secondary	Localize brain areas involved in movement	Localize brain areas involved in movement using high-density EEG recordings	60 - 90 minutes
Secondary	Localize brain areas involved in sensation	Localize brain areas involved in sensation using high-density EEG recordings	60 - 90 minutes
Secondary	Localize brain areas involved in emotion	Localize brain areas involved in emotion using high-density EEG recordings	60 - 90 minutes
Secondary	Localize brain areas involved in memory	Localize brain areas involved in memory using high-density EEG recordings	60 - 90 minutes
Secondary	Localize brain areas associated with lesions	Localize brain areas associated with lesions using high-density EEG recordings	60 - 90 minutes