Healthy Clinical Trial
Official title:
Comparison of Two Commercially Available Devices to Measure Nitric Oxide Lung Diffusing Capacity in Healthy, Non-smoking Adults
The measurement of nitric oxide lung diffusing capacity (DLNO) has been recently
standardised. To date, two pulmonary function devices are commercially available and are used
for the measurement of DLNO. No previous study assessed differences in gas exchange outcomes
(e.g., DLNO values) between both devices.
The aim of this project is to compare two commercially available devices that measure lung
diffusing capacity for nitric oxide (DLNO).
1. "MasterScreenTM" (PFT Pro, Jaeger, CareFusion, Hoechberg, Germany
2. "HypAir" ("HA", Medisoft, Dinant, Belgium).
In a single-center, crossover study conducted at the University Hospital Zurich, Switzerland,
35 healthy, non-smoking adults (>=18 years) will be invited to perform DLNO measurements in
random order using the MasterScreenTM (PFT Pro, Jaeger, CareFusion, Hoechberg, Germany) and
HypAir (Medisoft, Dinant, Belgium) devices during one study visit.
The order of the tests on the MasterscreenTM and HypAir devices will be randomly allocated
using central randomisation.
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