The Effect of Exercise on Pain Sensitivity in a Population With Ongoing Neck Pain Compared to Healthy Controls

Healthy Clinical Trial

Official title:

The Effect of Exercise on Neck Pain and Pain Sensitivity

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT03992495
• Other study ID #: N-20180063_Sub-project_3
• Status: Not yet recruiting
• Start date: June 20, 2019
• Est. completion date: January 2021

Study information

• Verified date: June 2019
• Source: Aalborg University
• Contact: Steffan W Christensen, PhD
• Phone: 99408889
• Email: stc[@]hst.aau.dk
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This study investigates the effect of exercise on pain sensitivity in ongoing neck pain patients compared to a healthy control group.

Description:

Increased pain sensitivity is a common finding in neck pain patients when compared to healthy controls. Although most studies favor exercise as an intervention, the specific effect on pain sensitivity is still debated. This study will investigate the effect of exercise on pain sensitivity in neck pain patients compared to healthy controls

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 46
• Est. completion date: January 2021
• Est. primary completion date: October 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 50 Years

Eligibility

Inclusion Criteria: - Healthy participants

• Pain free healthy participants

• Able to speak, read and understand Danish and English

Exclusion Criteria: - Healthy participants

• Pain from the neck or shoulder area during the past 6 months

• Experience of delayed onset muscle soreness (DOMS) during the week leading up to the test session

• Former surgery in neck or shoulder

• Current or previous chronic or recurrent pain condition

• Pregnancy

• Drug addiction defined as the use of cannabis, opioids or other drugs

• Previous neurologic, musculoskeletal or mental illnesses

• Regular use of analgesics

• Abnormally disrupted sleep in the last 24 hours preceding the experiment

• Lack of ability to cooperate

Inclusion Criteria: - Neck pain population

• Self reported neck pain lasting three months or longer.

• Able to speak, read and understand Danish and English

• Reduced/painful active range of motion of the head and/or painful reaction to palpation of the neck at the time of inclusion

Exclusion Criteria: - Neck pain population

• Shoulder pain during arm movements

• Experience of DOMS during the week leading up to the test session

• Former surgery in neck or shoulder

• Current or previous chronic or recurrent pain condition other than neck pain

• Pregnancy

• Drug addiction defined as the use of cannabis, opioids or other drugs

• Previous neurologic, musculoskeletal or mental illnesses

• Abnormally disrupted sleep in the 24 hours preceding the experiment

• Lack of ability to cooperate

Related Conditions & MeSH terms

• Healthy
• Hypersensitivity
• Neck Pain

Intervention

Other:
• Exercise
All participants will be exposed to aerobic/strengthening exercises

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Aalborg University

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	Change in body movements	Head repositioning accuracy will be tested using a clinical test in a seated position. Participants will turn their head to end of range in from a neutral position with their eyes closed and return to the start position again. The difference between start and end position will be recorded. Standing balance will be assessed by recording the time (seconds) a tandem stance can be maintained.	Baseline, 6 weeks, 12 weeks
Primary	Change in pain sensitivity	Pain sensitivity will be estimated by determining the pressure pain threshold (PPT) on the neck before and after exercise	Baseline, 6 weeks, 12 weeks
Secondary	Change in perceived pain	Pain will be scored using a scale from 0-10 with 0 being no pain and 10 being worst imaginable pain and by drawing perceived painful areas on a body charts	Baseline, 6 weeks, 12 weeks
Secondary	Change in disability	Disability will be estimated by scoring the Neck Disability Index (NDI) questionnaire. The questionnaire is designed to help express how neck pain affects your ability to manage everyday activities.(Domains: pain intensity, personal care, lifting, reading, headache, concentration, work, driving, sleeping, recreation). Higher score = high level of disability	Baseline, 6 weeks, 12 weeks