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Xanthohumol Metabolism and Signature — XMaS  

Healthy Clinical Trial

Official title:
Xanthohumol Metabolism and Signature (XMaS) in Healthy Adults

Clinical Trial Summary

A pilot study to assess the safety and tolerability of oral xanthohumol in humans, to identify a biological signature of xanthohumol exposure, and to characterize the role of xanthohumol metabolism by intestinal microorganisms in that signature.

Clinical Trial Description

This is a double-masked, placebo controlled, randomized clinical trial of xanthohumol, which is a constituent of hops (Humulus lupulus). Hops and its constituents have a long history of use for a variety of conditions. However, knowledge is limited regarding the measurable biological markers of human exposure, and the role of xanthohumol metabolism by microorganisms present in the gut. This information is necessary for the development of xanthohumol as a potential therapeutic intervention in conditions such as inflammatory bowel disease. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03735420
Study type Interventional
Source National University of Natural Medicine
Contact
Status Active, not recruiting
Phase Phase 1
Start date August 12, 2019
Completion date December 31, 2024
View Details
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