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Effects and Mechanisms of Melatonin on Blood Pressure, Insulin Resistance, and Platelets

Healthy Clinical Trial

Official title:
Effects and Mechanisms of Melatonin on Blood Pressure, Insulin Resistance, and Platelets

Clinical Trial Summary

The investigators will be studying the effect of melatonin on blood pressure, insulin resistance, and platelets, along with possible reasons for how melatonin cases these effects.

Clinical Trial Description

The investigators will be studying the effect of melatonin on blood pressure and insulin resistance, and possible reasons for how melatonin works on blood pressure and IR. Along with blood testing to measure adipokines, insulin resistance (IR), and platelet function (how well your blood clots), 24-hour ambulatory blood pressure monitoring (ABPM) will be used to measure blood pressure, since ABPM is the gold standard (best method) for accurate assessment of blood pressure status and associated cardiovascular risk. Vascular (blood vessel) function, IR, adipokine levels and sleep quality will also be measured. All study endpoints will be measured at baseline and following 6 weeks of daily melatonin 9 mg dosing. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03178396
Study type Interventional
Source Thomas Jefferson University
Contact
Status Completed
Phase N/A
Start date December 7, 2015
Completion date August 9, 2016
View Details
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