Healthy Clinical Trial
Official title:
Targeting Top-down and Bottom-up Processing in Eating Disorders Using Computerized Training Approaches: A Multimodal Outcome Study
Verified date | October 2019 |
Source | King's College London |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
This research project aims to explore the effectiveness of combined go/no-go training and
implementation intentions in targeting binge eating frequency among people with binge eating
disorder and bulimia nervosa.
The full intervention is 4 weeks long and consists of completing the training and food
diaries every day and meeting with the researcher twice for EEG recording. Moreover, it
involves completing questionnaires at baseline, at intervention completion, and one month
after the intervention.
Moreover, healthy control participants will be recruitment to complete baseline
questionnaires and take part in one EEG recording session in order to assess baseline
differences in brain activation in response to computer tasks.
Status | Completed |
Enrollment | 120 |
Est. completion date | June 1, 2019 |
Est. primary completion date | June 1, 2019 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 60 Years |
Eligibility |
Inclusion Criteria: 1) Diagnosis of an Eating Disorder (Bulimia Nervosa or Binge Eating Disorder); 2) No severe psychiatric comorbidity (e.g. psychosis); 3) Fluency in English; 4) No visual impairment; 5) No cognitive/neurological impairment; 6) No drugs or alcohol abuse; 7) No use of weight-loss medication; 8 No metabolic disorder; 9) Above 18 years old and below 60 years old. Exclusion Criteria: 1) No diagnosis of an eating disorder; 2) Severe psychiatric comorbidity; 3) No English language fluency; 4) Visual impairment (not correctable with eye-wear); 5) Cognitive/neurological impairment; 6) Drug or alcohol abuse; 7) Use of weight-loss medication; 8) A metabolic disorder; 9) Below 18 years old and above 60 years old. |
Country | Name | City | State |
---|---|---|---|
United Kingdom | Eating Disorders Unit, Institute of Psychiatry, Psychology, and Neuroscience | London |
Lead Sponsor | Collaborator |
---|---|
King's College London | University of Exeter |
United Kingdom,
Fairburn, C. G. (2008). Cognitive behavior therapy and eating disorders. Guilford Press
Hunot C, Fildes A, Croker H, Llewellyn CH, Wardle J, Beeken RJ. Appetitive traits and relationships with BMI in adults: Development of the Adult Eating Behaviour Questionnaire. Appetite. 2016 Oct 1;105:356-63. doi: 10.1016/j.appet.2016.05.024. Epub 2016 May 20. — View Citation
Kliemann N, Beeken RJ, Wardle J, Johnson F. Development and validation of the Self-Regulation of Eating Behaviour Questionnaire for adults. Int J Behav Nutr Phys Act. 2016 Aug 2;13:87. doi: 10.1186/s12966-016-0414-6. — View Citation
Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001 Sep;16(9):606-13. — View Citation
Lowe MR, Friedman MI, Mattes R, Kopyt D, Gayda C. Comparison of verbal and pictorial measures of hunger during fasting in normal weight and obese subjects. Obes Res. 2000 Nov;8(8):566-74. — View Citation
Whiteside, S. P., & Lynam, D. R. (2001). The Five Factor Model and impulsivity: Using a structural model of personality to understand impulsivity. Personality and Individual Differences, 30(4), 669-689. http://dx.doi.org/10.1016/S0191-8869(00)00064-7.
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Change in eating disorder symptomatology | Decrease in binge eating frequency and decrease in compensatory behaviours. | This will be assessed at baseline, intervention completion, and follow-up (1 month later) | |
Secondary | Change in weight/BMI | Weight will be measured by the researcher and BMI will be calculated. | This will be assessed at baseline (Time 0), intervention completion (4 weeks), and follow-up (8 weeks) | |
Secondary | Change in inhibitory control | This will be assessed using the self-report measure of disinhibition and using the go/no-go computerized task. | This will be assessed at baseline (Time 0) and intervention completion (4 weeks). | |
Secondary | Change in anxiety and depression symptoms | This will be assessed using the GAD and PHQ measures. | This will be assessed at baseline (Time 0), intervention completion (4 weeks), and follow-up (8 weeks) | |
Secondary | Changes in High Calorie Food Valuation | This will be assessed using the food rating task. | This will be assessed at baseline (Time 0) and post-intervention (4 weeks). | |
Secondary | Changes in Low Calorie Food Valuation | This will be assessed using the food rating task. | This will be assessed at baseline (Time 0) and post-intervention (4 weeks). |
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