Healthy Clinical Trial
Official title:
Effects of Synchronised Auditory Stimulations of the Sleep Slow Oscillation on Deep Sleep
This monocentric, cross-over, randomised, double blind and placebo-controlled study evaluates the effects of auditory stimulations of the sleep slow oscillation on deep sleep quality.
Sleep quality impairment has long been identified as a risk factor to develop
cardio-vascular, metabolic and more recently neurodegenerative diseases. The slow wave
sleep, characterized by slow oscillations, has a major role on memory and hormones
releasing. Here, we aim to assess a miniaturized sleep device that would automatically
detect and stimulate sleep slow oscillations with sounds to enhance deep sleep quality.
The subjects realize 3 conditions :
- Up condition : Auditory stimulations are delivered in synchrony with the up phase of
slow oscillations during N3 sleep stage.
- Random condition : Auditory stimulations are randomly delivered during N3 sleep stage.
- Placebo condition: The device is worn without any auditory stimulations delivered.
The subjects are equipped with a reference polysomnography and the auditory stimulation
device during 3 nights and one habituation night prior to them. A wash out period of 6 days
between each night will be respected.
;
Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Basic Science
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