Various Serving Sizes of Lentils on Blood Glucose and Insulin

Healthy Clinical Trial

Official title:

The Effect of Various Serving Sizes of Lentils and Other Starchy Meals on Post Prandial Blood Glucose Response and Insulin

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02940158
• Other study ID #: 16AU001
• Status: Completed
• Phase: N/A
• Start date: October 2016
• Est. completion date: January 8, 2018

Study information

• Verified date: May 2018
• Source: University of Guelph
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to assess the effects of consuming either 1/2 or 1/4 cup servings of lentils on post-prandial blood glucose and insulin as compared to 4 types of starchy foods (corn, macaroni, white potato, white rice).

Description:

Eligible participants will undergo a total of 6 study visits. During each visit, a fasted blood sample will be taken by fingerprick, and approximately 500 µL of blood will be dripped into a collection tube. The participant will then consume a meal of either: two types of lentils, corn, macaroni, white rice, or white potato. All study days will be randomized. Each meal will be served in either 1/4 or 1/2 cup servings depending on the study block. Six more blood samples will be taken by fingerprick at 15, 30, 45, 60, 90 and 120 minutes after the beginning of the meal.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 48
• Est. completion date: January 8, 2018
• Est. primary completion date: January 8, 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 40 Years

Eligibility

Inclusion Criteria

• Healthy men and women

• Age 18-40 years

• Body mass index (BMI) 20-30 kg/m2

Exclusion Criteria:

• Tobacco use

• Pregnant or breastfeeding

• Fasting blood glucose = 7.0 mmol/L

• Two hour blood glucose = 11.1 mmol/L after consuming 75g glucose drink (Oral Glucose Tolerance Test beverage)

• Any major medical condition including a history of AIDS or hepatitis

• Medical or surgical event requiring hospitalization within 3 months of randomization

• Any medications except a stable dose (3 months) of oral contraceptives, blood pressure or statin medications

• Blood pressure >140/90 mm Hg

• Natural health products (NHPs) used for glycemic control

• Probiotic supplements

• Dietary fibre supplements

• Consumption of >4 servings of pulses per week

• Food allergy or non-food life threatening allergy

• Shift workers

• Alcohol consumption >14 drinks/week or >4 drinks/sitting

• Recent or intended significant weight loss or gain (>4 kg in previous 3 months)

• Elite athletes

Related Conditions & MeSH terms

• Healthy

Intervention

Other:
• 1/4 cup- Small red lentil

• 1/4 cup- Small green lentil

• 1/4 cup- corn

• 1/4 cup- macaroni

• 1/4 cup- white potato

• 1/4 cup- white rice

• 1/2 cup- small red lentil

• 1/2 cup- small green lentil

• 1/2 cup- corn

• 1/2 cup- macaroni

• 1/2 cup- white potato

• 1/2 cup- white rice

Locations

Country	Name	City	State
Canada	Human Nutraceutical Research Unit	Guelph	Ontario

Sponsors (3)

Lead Sponsor	Collaborator
University of Guelph	Agriculture and Agri-Food Canada, Saskatchewan Pulse Growers

Country where clinical trial is conducted

Canada, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Postprandial Blood Glucose		2 hours Postprandial
Primary	Postprandial Blood Insulin		2 hours postprandial