Biobank Based on the i-Share Student Cohort

Healthy Clinical Trial

— bio-Share  

Official title:

Biobank Based on the i-Share Student Cohort

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02568371
• Other study ID #: CHUBX2015/07
• Status: Completed
• Start date: October 6, 2015
• Est. completion date: November 30, 2017

Study information

• Verified date: March 2019
• Source: University Hospital, Bordeaux
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The bio-Share project aims at collecting blood samples in students participating in the i-Share cohort (www.i-share.fr). Investigators aim at setting up a platform that will enable investigators in the future to study biological determinants of conditions that affect young adults and to test certain hypotheses on the pathophysiology and mechanisms underlying diseases occurring both at a young age and later in life (as early exposures may also impact late onset diseases)

Description:

The i-Share cohort was set up to study various important aspects of students' health and to better understand early mechanisms contributing to the occurrence of common diseases representing an important public health burden. The i-Share cohort is funded by an "investment for the future grant" from the French National Research Agency (ANR-10-COHO-05-01) with the aim to recruit 30000 students at the University of Bordeaux, and a few additional partner universities in France and abroad (www.i-share.fr).

The bio-Share study is a biological repository embedded within the i-Share study, aiming at collecting blood samples (for genetic analyses as well as measurement of other biomarkers) from a subset of 2000 i-Share participants volunteering for this ancillary project.

The goal is to set up a platform that will enable investigators in the future to study biological determinants of conditions that affect young adults and to test certain hypotheses on the pathophysiology and mechanisms underlying diseases occurring both at a young age and later in life (as early exposures may also impact late onset diseases).

The biobank will comprise the following biological materials: plasma, serum, whole blood, red blood cells, DNA, RNA. Levels of fasting glucose and lipid levels (total cholesterol, HDL-cholesterol, LDL-cholesterol, triglycerides) will be returned to participants.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 1997
• Est. completion date: November 30, 2017
• Est. primary completion date: November 30, 2017
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Be an i-Share participant in Bordeaux

• Being aged 18 years or more

• Being affiliated or beneficiary of a social security

• Having filled out the first online i-Share questionnaire

• Having signed a written informed consent

Exclusion Criteria:

• Pregnant or breastfeeding women,

• Persons who cannot personally give their consent and adults under guardianship.

Related Conditions & MeSH terms

• Healthy

Locations

Country	Name	City	State
France	Centre Hospitalier Universitaire de Bordeaux - PELLEGRIN	Bordeaux	Aquitaine

Sponsors (2)

Lead Sponsor	Collaborator
University Hospital, Bordeaux	National Research Agency, France

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The acquisition date of blood samples		Day 1
Primary	The number of the aliquots for each of the stored biological samples		Day 1
Primary	The total volume of the aliquots for each of the stored biological samples		Day 1
Secondary	Glucose (fasting)		Day 1
Secondary	Total cholesterol (fasting)		Day 1
Secondary	High-density lipoprotein cholesterol (fasting)		Day 1
Secondary	Low-density lipoprotein-cholesterol (fasting)		Day 1
Secondary	Triglycerides (fasting)		Day 1