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NCT01988545 Clinical Trial

GLP-1's Effect on Cardiac Parameters and Mesenteric Blood Flow

Healthy Clinical Trial

Official title:
GLP-1's Influence on Intestinal Blood Flow

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT01988545
Other study ID # 2013.GLP-1
Secondary ID
Status Recruiting
Phase N/A
First received November 13, 2013
Last updated November 19, 2013
Start date November 2013
Est. completion date December 2014

Study information
Verified date November 2013
Source University Hospital Koge
Contact Lasse Bremholm, MD, ph.d.
Phone 0004560927874
Email lassebremholm@dadlnet.dk
Is FDA regulated No
Health authority Denmark: Ministry of Health
Study type Interventional

Clinical Trial Summary

to investigate the effect of the human incretin hormone GLP-1 on mesenteric blood flow and cardiac parameters

Description:

to investigate the effect of the human incretin hormone GLP-1 on mesenteric blood flow and cardiac parameters, in healthy subjects, 4 arms, task force monitor

Recruitment information / eligibility
Status Recruiting
Enrollment 8
Est. completion date December 2014
Est. primary completion date June 2014
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group 20 Years to 80 Years
Eligibility Inclusion Criteria:

- healthy subjects

Exclusion Criteria:

- medical conditions

Study Design

Allocation: Randomized, Endpoint Classification: Pharmacodynamics Study, Intervention Model: Single Group Assignment, Masking: Double Blind (Subject, Outcomes Assessor), Primary Purpose: Basic Science

Related Conditions & MeSH terms

Intervention

Other:
• 1,5 nmol/kg,GLP-1 sc injection

• 1,5 nmol/kg GLP-1 9-36amide, sc injection

• Exendin-4 ;10 ug,sc injection

• saline

Locations
Country Name City State
Denmark Køge Hospital Køge State...

Sponsors (3)
Lead Sponsor Collaborator
University Hospital Koge Glostrup University Hospital, Copenhagen, University of Copenhagen

Country where clinical trial is conducted

Denmark, 

Outcome
Type Measure Description Time frame Safety issue
Other cardiac parameters measure of cardiac change with task force monitor with in 120 minutes No
Primary blood flow blood flow change measured by ultra sound with in 120 minutes No
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