Healthy Clinical Trial
Official title:
Dose and Response of Dietary and Inorganic Nitrate in Healthy and Active Men
It was shown by some researchers that dietary nitrate such as beet root juice can lower
oxygen consumption in men and act as a performance enhancing supplement.
It was not shown, what the optimal dosage is and if there is any difference in oxygen
consumption comparing beet root juice and inorganic nitrate.
Therefore, the aim of the study is to conduct a study ingesting different sodium nitrate and
beet root juice dosages. We would measure nitrate and nitrite concentrations in the blood at
different time points and the subjects have to perform an exercise test measuring oxygen
consumption 3 hours after the ingestion of nitrate.
1. The subjects have to ingest 7 different dosages of either beetroot juice or sodium
nitrate on seven different occasions. Every hour a blood withdrawal is taken to measure
nitrate and nitrite concentration in the blood.
2. The subjects have to ingest 7 different dosages of either beetroot juice or sodium
nitrate on seven different occasions. Three hours after the intake of the supplement
the subjects have to perform an exercise test on a bicycle. They have to cycle 5 min at
50% of maximal oxygen consumption and 8min at 80% of maximal oxygen consumption
separated by a 5min break. Oxygen consumption would be measured during the whole
exercise test. Blood withdrawal is taken before the ingestion, after 3 hours and after
the test.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Factorial Assignment, Masking: Double Blind (Subject, Caregiver, Outcomes Assessor), Primary Purpose: Treatment
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