Healthy Clinical Trial
Official title:
Glycemic and Insulinemic Index Determination of 2 Products: Fructilight® and A Fruit Fructo-Oligosaccharides in Sweet Matrix
The aim of the study is to determine glycemic and insulinemic index of 2 sweet syrups : FructiLight® and fruit Fructo-oligosaccharides in sweet matrix compared to glucose.
12 male and female healthy adults are included in the study. During 5 separated visits
subjects consume either 50 g of glucose in water (3 glucose response tests) or portion of
syrup supply the equivalent of 50 g of glycaemic carbohydrates (2 syrup response tests).
Experimental sessions last 3 hours with 9 veinous and capillary blood taking. The
experimental meals are served at t0 and are consumed between 12 and 15 minutes maximum. At
time -5, 0, 15, 30, 45, 60, 90, 120 and 180 minutes, glucose is measured out on capillary
blood and insulin is measured out on venous blood.
The glycemic index and Insulinemic index determination of the 2 syrups start by the
calculation for each glycemia and insulinemia responses of the AUC over 120 min. The
AUC(0-120min) is computed following the FAO recommendation (cf. FAO/WHO 1998), i.e. using
the trapezoidal incremental method and not taking into account the area beneath the fasting
concentration. then GI and II values expressed in percentage are calculated by dividing the
AUC(0-120min) for test syrup products by the AUC(0-120min) for the glucose reference and
multiplying by 100.
;
Allocation: Randomized, Endpoint Classification: Bio-availability Study, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Basic Science
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