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Clinical Trial Summary

The overall goal of this project is to understand how a mother's health at conception may influence her child's growth and development.


Clinical Trial Description

The purpose of this study is to determine how the mother's health prior to or at the beginning of pregnancy may influence her child's growth and development. We plan to: 1) longitudinally and simultaneously assess a true measure of body composition (lean and fat mass) of the offspring, assess body composition of both parents, and obtain dietary intake data of the mother and offspring; 2) determine endocrine and metabolic profiles of the mother at baseline (pre-conception), during pregnancy and at birth (such as insulin, glucose, leptin); 3) determine the energy expenditure and physical activity of the mother and the child; 4) determine gene expression of the placenta and umbilical cord via gene microarray and real time PCR; and 5) focused on appropriate-for-gestational age (AGA) infants (the majority of infants born from normal and overweight mothers).Accordingly, this study will provide much needed comprehensive information on the possible effect of fetal programming on the development of pediatric obesity. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT01131117
Study type Observational
Source Arkansas Children's Hospital Research Institute
Contact
Status Active, not recruiting
Phase
Start date April 2, 2010
Completion date August 2024

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