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Autonomic Nervous System Activity, Aging and Sleep Apnea/Hypopnea — SYNAPSE  

Healthy Clinical Trial

Official title:
Autonomic Nervous System Activity, Aging and Sleep Apnea/Hypopnea in a Prospective Cohort of Subjects Aged 67 Years

Clinical Trial Summary

The regulatory effects of the autonomic nervous system (ANS) concern almost all organs which permanently feed information back to this global biological vigilance system controlling allostasis. Heart rate fluctuations are highly dependent on ANS control, making the heart one of the best indicators of ANS activity. Low ANS activity level is associated with severe cardiac and cerebral events, as well as to death from any cause in the general population. It is even associated with sleep apnea/hypopnea.

Clinical Trial Description

The main goal of this SYNAPSE study is to evaluate, on a selected prospective cohort of subjects aged 67 years upon study entry, the incidence of sleep apnea/hypopnea and the prognostic values of ANS activity levels measured at preset times and of cardiovascular or cerebrovascular events. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00766584
Study type Observational
Source Centre Hospitalier Universitaire de Saint Etienne
Contact
Status Active, not recruiting
Phase
Start date January 15, 2003
Completion date December 2026
View Details
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