Effect of Hypnosis on Motor Cortex Excitability

Healthy Clinical Trial

Official title:

Effect of Hypnosis on Motor Cortex Excitability

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00416247
• Other study ID #: rambam2409_CTIL
• Status: Completed
• Phase: N/A
• First received: December 26, 2006
• Last updated: August 4, 2010
• Start date: December 2006
• Est. completion date: June 2009

Study information

• Verified date: December 2006
• Source: Rambam Health Care Campus
• Contact: n/a
• Is FDA regulated: No
• Health authority: Israel: Ministry of Health
• Study type: Interventional

Clinical Trial Summary

This study is intended to investigate neurophysiological mechanisms of hypnosis using transcranial magnetic stimulation (TMS) and assessment of motor cortex excitability in healthy volunteers under hypnosis.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 20
• Est. completion date: June 2009
• Est. primary completion date: December 2007
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 20 Years to 45 Years

Eligibility

Inclusion Criteria: .

1. Healthy volunteers aged 20 to 45 years.

2. Hypnotisability above 14 as measured by the Tellegan absorption scale.

Exclusion Criteria:

1. Psychiatric diagnosis in axis I or axis II;

2. Documented history of head injury or seizure disorder;

3. Evidence of a disorder which could affect peripheral and central conduction such as multiple sclerosis, motor neuron disease, carpal tunnel syndrome, cervical spondylosis, diabetic neuropathy.

4. Any other contraindication to TMS as specified in the safety guidelines for rTMS (Wassermann, 1998) such as cardiac pacemakers or metallic deep brain electrodes.

5. Chronic pharmacological treatment.

Study Design

Allocation: Non-Randomized, Endpoint Classification: Pharmacodynamics Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic

Related Conditions & MeSH terms

• Healthy

Intervention

Behavioral:
• Hypnosis
Hypnosis

Locations

Country	Name	City	State
Israel	Rambam Medical Center	Haifa

Sponsors (1)

Lead Sponsor	Collaborator
Rambam Health Care Campus

Country where clinical trial is conducted

Israel, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Cortical Excitability		Before and after intervention	No