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Effects of Allergen Inhalation on Adenosine Receptor Expression in Sputum and Peripheral Blood

Healthy Clinical Trial

Official title:
Effects of Allergen Inhalation on Adenosine Receptor Expression and Mast Cell Activation in Peripheral Blood and Sputum of Asthmatics and Healthy Subjects

Clinical Trial Summary

The purpose of this study is to determine whether asthmatics have different adenosine receptor expression profiles than healthy controls. We hypothesize that asthmatics will have increased adenosine receptor expression versus control subjects.

We also want to study the effects of allergen inhalation on adenosine receptor expression in asthmatics. We believe that adenosine receptor expression will be upregulated after allergen inhalation.

Both hypotheses are being tested in sputum and peripheral blood.

Clinical Trial Description

n/a

Study Design

Observational Model: Defined Population, Primary Purpose: Screening, Time Perspective: Cross-Sectional

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00116311
Study type Observational
Source Groningen Research Institute for Asthma and COPD
Contact
Status Active, not recruiting
Phase N/A
Start date July 2005
Completion date February 2007
View Details
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