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NCT00005923 Clinical Trial

The Effect of Estrogen and Progesterone Levels on Knee and Ankle Joint Laxity

Healthy Clinical Trial

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT00005923
Other study ID # NCRR-M01RR00109-0749
Secondary ID M01RR000109
Status Active, not recruiting
Phase N/A
First received June 23, 2000
Last updated June 23, 2005

Study information
Verified date November 2001
Source National Center for Research Resources (NCRR)
Contact n/a
Is FDA regulated No
Health authority United States: Federal Government
Study type Observational

Clinical Trial Summary

The proposed research is an observational study designed to compare estrogen and progesterone serum levels with knee and ankle joint laxity, and muscle reaction time as a measure of neuromuscular function. Three groups of women athletes with differing estrogen and progesterone profiles (normal menstrual cycles, amenorrheic, and exogenous estrogen supplementation) and one control group (male collegiate athletes) will be used to compare differences in joint laxity and neuromuscular function. Blood levels of estrogen and progesterone will be measured at four time points across the menstrual cycle. Joint laxity and muscle reaction time will also be measured at each of these points. The investigator hypothesizes that knee and ankle joint laxity and muscle reaction time will significantly increase with increasing estrogen and progesterone levels.

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 0
Est. completion date
Est. primary completion date
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group 15 Years to 23 Years
Eligibility Inclusion Criteria:

- pre-collegiate or collegiate athletes

Study Design

Observational Model: Natural History

Related Conditions & MeSH terms

Locations
Country Name City State
United States University of Vermont Burlington Vermont

Sponsors (1)
Lead Sponsor Collaborator
National Center for Research Resources (NCRR)

Country where clinical trial is conducted

United States, 

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