Healthy Clinical Trial
Official title:
Hemispheric Lateralization of Language Receptive Function in the Deaf and in Hearing Individuals Who Learned ASL as First Language
The human brain is made up of two halves called hemispheres. Each half of the brain is
responsible for processing different kinds of information. Previous neuroimaging studies
have shown that both the right and left hemispheres are involved when processing information
given in American Sign Language (ASL). However, the study also showed that when processing
spoken language, the left hemisphere was mostly involved.
Researchers would like to find out more about how the brain processes American Sign Language
(ASL). This study is designed to determine if the right hemisphere is necessary for normal
understanding of ASL.
Status | Completed |
Enrollment | 30 |
Est. completion date | December 2000 |
Est. primary completion date | |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Both |
Age group | N/A and older |
Eligibility |
Subject age between 18 and 65 years. Adult hearing offsprings of deaf parents. Congenitally deaf individuals. Intact hearing volunteers. No subjects with personal or family history of seizures or other neurological or demyelinating disorders. No pregnant women tested after urine pregnancy test. No subjects with severe coronary disease. No subjects with metal in the cranium except mouth. No subjects with intracardiac lines and implanted medication pumps. No subjects with increased intracranial pressure as evaluated by clinical means. No subjects with cardiac pacemakers. No subjects with an intake of neuroleptics. |
N/A
Country | Name | City | State |
---|---|---|---|
United States | National Institute of Neurological Disorders and Stroke (NINDS) | Bethesda | Maryland |
Lead Sponsor | Collaborator |
---|---|
National Institute of Neurological Disorders and Stroke (NINDS) |
United States,
Cohen LG, Bandinelli S, Sato S, Kufta C, Hallett M. Attenuation in detection of somatosensory stimuli by transcranial magnetic stimulation. Electroencephalogr Clin Neurophysiol. 1991 Oct;81(5):366-76. — View Citation
Neville HJ, Bavelier D, Corina D, Rauschecker J, Karni A, Lalwani A, Braun A, Clark V, Jezzard P, Turner R. Cerebral organization for language in deaf and hearing subjects: biological constraints and effects of experience. Proc Natl Acad Sci U S A. 1998 Feb 3;95(3):922-9. — View Citation
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