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Healthy Adults clinical trials

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NCT ID: NCT04908995 Completed - Healthy Adults Clinical Trials

Safety, Tolerability, Pharmacokinetics and Food Effects of Oral EC5026 in Healthy Subjects

Start date: April 30, 2021
Phase: Phase 1
Study type: Interventional

The purpose of the study is to provide safety, tolerability, pharmacokinetics and food effects data of a single 8 mg oral dose of EC5026 in healthy subjects.

NCT ID: NCT04845464 Completed - Healthy Adults Clinical Trials

Sleep Quality and Cognition in Young Adults

Start date: March 8, 2019
Phase:
Study type: Observational

Sleep quality is impaired in young adults due to current conditions. Recent studies emphasize that this situation may also affect the cognitive status of individuals. The aim of this study was to investigate the relationship between sleep quality and cognitive status in young adults. A total of 122 young adults (61 female, 61 male) aged between 18 to 25 and studied at Istanbul Medipol University, Faculty of Health Sciences, were included in the study. Individuals were evaluated with "Pittsburgh Sleep Quality Index (PSQI)" for sleep quality; with "Montreal Cognitive Status Scale (MoCA)" for cognitive status, with "STROOP Test" for selective attention; with "Verbal Fluency Test" for sustained attention; with "WMS-R digit Span Test" for auditory attention

NCT ID: NCT04800614 Completed - Healthy Adults Clinical Trials

A Study to Explore the Effect of Food Before a Single Dose of Sitravatinib

Start date: March 15, 2021
Phase: Phase 1
Study type: Interventional

An Open-label, Randomized, Three-period, Crossover Study of the Effect of Food on the Pharmacokinetics of a Single Oral Dose of Sitravatinib in Healthy Adult Subjects

NCT ID: NCT04759612 Completed - Healthy Adults Clinical Trials

Is Self-action Observation More Effective Than Observing Another Person's Action?

Start date: June 4, 2021
Phase: N/A
Study type: Interventional

The aim of the study is to compare the possible effects of self-action observation and observation of another person's action on upper extremity functionality, cognitive functions and reaction times.

NCT ID: NCT04724304 Completed - Healthy Adults Clinical Trials

Myocardial Blood Volume Measurement by Real-Time Myocardial Perfusion Echocardiography Correlates to Myocardial Compressibility by Cardiac Magnetic Resonance Imaging in Healthy Subjects

Start date: February 9, 2021
Phase: N/A
Study type: Interventional

This study is being done to find out the normal amount of blood within the heart muscle and the variations in this blood flow between a cardiac MRI and TTE.

NCT ID: NCT04666181 Completed - Healthy Adults Clinical Trials

Cortical Activation and Cognitive-Motor Learning

Co-ACT&LEARN
Start date: January 15, 2021
Phase: N/A
Study type: Interventional

The purpose of this research study is to assess the effects of dual-task training using a dynamic balance task and an auditory reaction time task on dual-task performance in healthy young adults and to assess the cortical activity within the prefrontal and sensorimotor cortices in response to dual-task training using functional near infrared spectroscopy (fNIRS).

NCT ID: NCT04596709 Completed - Healthy Adults Clinical Trials

Investigation of Blood Glucose and Insulin Response After Intake of Vitalose

Start date: October 22, 2020
Phase: N/A
Study type: Interventional

The aim of this study is to assess the postprandial glucose and insulin response of Vitalose.

NCT ID: NCT04573426 Completed - Obesity Clinical Trials

Pain and Acetaminophen in Women Study

PAWS
Start date: November 15, 2019
Phase:
Study type: Observational

The purpose of this study is to evaluate the influence of acetaminophen on pain response and inflammation.

NCT ID: NCT04492631 Completed - Healthy Adults Clinical Trials

Safety of an Oral Probiotic in Healthy Adults

Start date: July 28, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the safety of an oral probiotic in healthy individuals.

NCT ID: NCT04339972 Completed - Healthy Adults Clinical Trials

Low Intensity Focused Ultrasound Pulses (LIFUP) to Modulate Pain

Start date: February 1, 2019
Phase: N/A
Study type: Interventional

The anterior nuclei of the thalamus in addition to periaqueductal gray (PAG) and rostral ventromedial medulla (RVM) are integral regions of a supraspinal opioidergic structure that regulate pain perception. With the capability to influence deep neurological tissues, low intensity frequency ultrasound pulsation (LIFUP) can likely modulate this circuit and induce analgesia. LIFUP deep brain modulation is achieved by induction of focused mechanical waveforms that traverse the cranium and underlying brain tissue. The low frequency of the ultrasonic wave consequently alters neuronal transmission and causes action potential variations through mechanical means, rather than thermal. The purpose of this study is to examine whether stimulation of the anterior nuclei of the thalamus via LIFUP induces analgesia. We hypothesize that suppression of the anterior nuclei of the thalamus will induce a temporary increase in pain tolerance. Moreover, the behavioral changes in pain will correlate with specific regional BOLD changes during pain.