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Healthy Adults clinical trials

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NCT ID: NCT06227832 Active, not recruiting - Healthy Adults Clinical Trials

A Study to Determine the Effect of KP-001 on Metformin and Midazolam Pharmacokinetics and the Effect of Clarithromycin on KP-001 Pharmacokinetics in Healthy Adult Participants

Start date: December 15, 2023
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine the Effects of KP-001 on Metformin (a substrate of MATE1) and Midazolam (a substrate of CYP3A4) Pharmacokinetics and the Effect of Clarithromycin (potent CYP3A4/P-gp Inhibitor) on KP-001 Pharmacokinetics in Healthy Adult Participants. The study will also evaluate the safety and tolerability of KP-001 with and without a single dose or multiple doses of an interaction drug. The study comprises 3 parts. Participants will stay in the Clinical Unit during the study, depending on which part they assigned to. Participants will remain at the clinical site for a 13 day/12 night in-house stay (Part 1), a 14 day/13 night in house stay (Part 2), or a 11 day/10 night in-house stay (Part 3).

NCT ID: NCT05128409 Active, not recruiting - Healthy Adults Clinical Trials

Phase I of XKH001Injection in Healthy Adults

Start date: March 7, 2023
Phase: Phase 1
Study type: Interventional

XKH001is a recombinant humanized monoclonal IgG1 antibody for subcutaneous injection. XKH001 specifically blocks interleukin-25 from binding to its receptors. To evaluate the safety, tolerability, pharmacokinetics (PK) of single ascending doses of XKH001 injection following subcutaneous administration

NCT ID: NCT04973722 Active, not recruiting - Healthy Adults Clinical Trials

A Study to Evaluate LY06006 and Prolia in Healthy Adults

Start date: December 9, 2020
Phase: Phase 1
Study type: Interventional

A randomized, double-blind, parallel-group study in Chinese healthy male subjects to evaluate the pharmacokinetics, pharmacodynamics, safety and immunogenicity of LY06006 versus Prolia following single-dose subcutaneous injection

NCT ID: NCT04844775 Active, not recruiting - Healthy Adults Clinical Trials

A Prophylactic HIV Vaccine Trial to Evaluate the Safety and Immunogenicity of HIV Clade C DREP Alone and in Combination With a Clade C ENV Protein in Healthy HIV-uninfected Adults

Start date: August 5, 2022
Phase: Phase 1
Study type: Interventional

EHVA P01 is an international, phase I, prophylactic HIV vaccine trial to evaluate the safety and immunogenicity of HIV Clade C DREP alone and in Combination with a Clade C ENV protein in healthy HIV-uninfected adults.

NCT ID: NCT04677920 Active, not recruiting - Healthy Adults Clinical Trials

The Healthy Cookie Energy Study: Understanding How Healthy Cookies Affect Mitochondrial Biology

HCES
Start date: September 7, 2020
Phase: N/A
Study type: Interventional

The proposed research is an intervention and feasibility pilot trial designed to determine if short-term consumption of healthy cookies made with an oil rich in linoleic acid can influence mitochondria biology in white blood cells and muscle. The hypothesis of the study is that consuming 1 healthy cookie rich in linoleic acid each day for two weeks will improve mitochondrial biology in white blood cells and muscle.

NCT ID: NCT04230057 Active, not recruiting - Healthy Adults Clinical Trials

Pharmacokinetics Study of Antitumor B in Healthy Volunteers

Start date: December 12, 2019
Phase:
Study type: Observational

The purpose of this study is to evaluate the single-dose oral pharmacokinetics of an herbal supplement - Antitumor B - in healthy subjects.

NCT ID: NCT03312920 Active, not recruiting - Healthy Adults Clinical Trials

Investigating Memory Retrieval Improvement in Healthy Subjects

Start date: September 27, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate whether learning can be accelerated and associative memory performance improved in healthy subjects by applying transcranial Direct Current Stimulation (tDCS) during a Face Name memory task.

NCT ID: NCT02841618 Active, not recruiting - Healthy Adults Clinical Trials

The Healthy Cookie Study: Understanding How Healthy Cookies Affect Fat in the Blood,

Start date: January 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to understand how consuming healthy cookies every day for two weeks will affect different types of fat in the blood. Specifically, the overall goal of this study is to find out if the healthy cookies can increase a polyunsaturated fat called linoleic acid in plasma, red blood cells and white blood cells.