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Health Behavior clinical trials

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NCT ID: NCT06051318 Not yet recruiting - Diabetes Clinical Trials

Relationship Between Individual Effect of Diet on Postprandial Glycemia and Gut Microbiome Profile in Healthy Subjects

Start date: January 2024
Phase: N/A
Study type: Interventional

When all the food we eat is digested, it will increase blood glucose. Two people can have different glucose blood levels to the same food and one reason can be bacteria live in our gut. There are more than a thousand bacteria species in our gastrointestinal tract that have an important role in the proper functioning of our body, so our gut microbiome is a key piece for our nutrition and blood glucose control. Nowadays, one of the major public health concerns is the rise of people with diabetes (a disease characterized by an increase in blood glucose) and the increase in obesity, in which one of several risks is diabetes. There are multiple reasons for people develop those diseases, however, some care on diet management can prevent, delay, or improve the effects of these illnesses. Therefore, this study proposes studying the blood glucose variation between healthy volunteers and if there is a relationship between that variation and the intestinal bacteria present. These results can help doctors and nutritionists elaborate a personalized diet for people who need blood glucose level control. The investigators are recruiting volunteers aged 18 to 60, healthy, living at Florianopolis and the surroundings to participate in this crossover randomized N-of-1 study. The participants must collect fecal samples. After collection, the participants will meet the investigators and receive a kit containing ten standardized breakfasts, with two kinds of muffins, and a kit containing a glucose monitor (Abbott Freestyle Libre-CE marked) to monitor their blood sugar levels. The volunteers must have breakfast with the standardized meals and monitor the fasting glucose blood and postprandial glucose blood levels for ten consecutive days. Besides, they must take notes (like a diet diary) about all the food they ingest during the day in ten days of the study.

NCT ID: NCT06046079 Not yet recruiting - HIV Clinical Trials

Predictors of Health Service Utilizations Among Key Population in Washington DC

Start date: September 15, 2023
Phase:
Study type: Observational

The primary objective of the proposed study is to investigate how PrEP use might result in an increase in the utilization of health and social services offered at a local community-based organization.Our primary hypothesis is that we will observe higher utilization of sexual health (STI screenings), psychosocial health (psychotherapy, and substance use treatment) and other social services (emergency cash assistance, food pantry, transportation assistance, clothing,and housing resources) among PrEP users (LAI-PrEP or daily oral) compared to participants who are PrEP naïve over the 12-month follow-up period.

NCT ID: NCT05952427 Not yet recruiting - Health Behavior Clinical Trials

Adverse Childhood Experiences and Infertility : ACESI

ACESI
Start date: August 1, 2023
Phase:
Study type: Observational

Adverse childhood experiences can have powerful effects on health and quality of life in adulthood. Thus, having a history of childhood trauma, before the age of 18 (physical aggression, sexual abuse, death of a close person, etc.) significantly increases the risk of having cancer, cardiovascular disease, psychological damage , or earlier mortality. Validated scores allow the evaluation of the importance of adverse childhood experiences, in particular the ACE score (adverse childhood experiences) published by Felitti. Studies on the subject show a dose-response relationship between exposure to adverse childhood experiences and negative outcomes in terms of health and well-being. The physiopathological tracks to explain the occurrence of somatic pathologies in adulthood include the observation of a state of hyper-activation of the HPA axis that persists in adulthood; modulations of immunity, but also epigenetic modifications. Some data are available on the associations between childhood trauma and obstetric risks, with a significant increase in the risk of preterm delivery and fetal death in utero. Primary objective : 1a) To study the prevalence of adverse childhood experiences (ACE) in women consulting for the first time in an PMA service for the desire to become pregnant, and 1b) To study the association between adverse childhood experiences and infertility in adulthood, by comparing infertile women with nulliparous control women in the general population consulting for their classic gynecological follow-up.

NCT ID: NCT05837468 Not yet recruiting - Health Behavior Clinical Trials

Better App: (Further-)Development and Evaluation of a Digital Lifestyle Programme

BETTERapp
Start date: May 11, 2023
Phase:
Study type: Observational

In recent years, we developed and evaluated personalised lifestyle interventions, the BETTER programmes (BETER in Dutch, acronym for Move, Eat, Change). Underlying principle for all BETER programmes is that people with the same condition may have different underlying causes, so-called subtypes. In this follow-up project with a mixed methods design, we aim to evaluate and optimise the subtype-questionnaire/algorithm (study 1, interrater reliabiliy) and evaluate the digitised BETER programme, the BETTER App (study 2, case series design with qualitative and quantitative evaluation). The main questions it aims to answer are: 1. What is the inter-rater reliability of two subtype experts and criterion validity of the symptom questionnaire compared with the experts for identifying overweight subtypes? 2. How is the BETER app used and rated (process evaluation)? To answer question 1, participants complete a questionnaire and have two interviews with two experts. To answer question 2, participants use the BETTERapp for 6 weeks and complete a usability questionnaire after 3 and 6 weeks and participate in 1 or 2 focus group interviews. This study contributes to optimising the Minimal Viable Product of the BETER app to finally reach a mature version.

NCT ID: NCT05732779 Not yet recruiting - Health Behavior Clinical Trials

Mobile Video Directly Observed Therapy (DOT) for Immunosuppression Medication Adherence in Adolescent Heart Transplant Recipients

Start date: March 31, 2024
Phase: N/A
Study type: Interventional

We will conduct a two-group randomized controlled trial to examine the eMocha DOT intervention with pediatric HT recipients.In this population, medication nonadherence remains a primary cause of late acute rejection (LAR) episodes, increased number of hospitalizations, graft failure, and patient mortality. Herein, we propose an innovative approach to promote medication adherence and improve patient and graft outcomes.

NCT ID: NCT05686889 Not yet recruiting - Health Behavior Clinical Trials

Post-Hoc Enthusiasm and Wariness

PHEW
Start date: May 1, 2023
Phase: N/A
Study type: Interventional

The post-hoc fallacy (also termed the post-hoc-ergo-propter-hoc fallacy) has been recognized for centuries with endless relevance. The general concept in medical care is that patients who improve after a treatment are not necessary patients who improve because of a treatment. Modern medicine provides multiple opportunities to examine such pitfalls of judgment due to the prevailing uncertainty, incompleteness of our understanding pathogenic mechanisms, and natural tendency to connect treatments to outcomes. In this study, we will investigate whether judgments about vitamin supplementation might demonstrate the post-hoc fallacy.

NCT ID: NCT05576987 Not yet recruiting - Health Behavior Clinical Trials

Student Behavior in School Accident Precautions

Start date: October 5, 2022
Phase: N/A
Study type: Interventional

Accidents are an important public health problem due to temporary or permanent disability and deaths. Injuries are among the most important causes of death and lifelong disability between the ages of 5-14. Children at these ages spend long hours at school and are physically very active in school. It is reported that 15% of child accidents occur at school. For this reason, it is important to increase the standard of knowledge of children to improve their behavior towards safety precautions. Purpose of this study is to research the impact of the education that has given towards the health belief model, for the behavior of children about precautions against school accidents. This study is Quasi-experimental study. There will a experiment and a control group in the study. Within the scope of the study, the researcher will train students about school accidents and how to prevent them for 30 minutes a week at the total of 4 weeks. No intervention will be applied to the control group. The scale will be applied to the students, before the training and afterwards to determine the behaviors of students towards safety precautions in school accidents.

NCT ID: NCT05539066 Not yet recruiting - Health Behavior Clinical Trials

AI Health Assistant and Type 2 Diabetes

Start date: October 1, 2022
Phase: N/A
Study type: Interventional

The developed health assistant has the functions of intelligent analysis of health data inside and outside the hospital, health reminder, etc. The advantages of AI health assistant management group compared with conventional management group in terms of comprehensive compliance rate, metabolic index level, hypoglycemia incidence rate was further studied.

NCT ID: NCT05317130 Not yet recruiting - Diabetes Clinical Trials

A Complex Health Promotion Intervention in Parasport - The Safe & Healthy Parasport Project

Start date: September 1, 2022
Phase:
Study type: Observational

The interest in Para sport is steadily increasing. A concern is, though, that elite Para athletes report a high incidence of injuries and illnesses. Altogether, there is an urgent need to prevent such incidents among athletes already suffering from an impairment. However, most of the existing training-based prevention programmes are not adapted or accessible to Para athletes. Also, recent research suggests that sports safety work advantageously should facilitate disease prevention and health promotion. Such intervention would hypothetically also have the potential to reduce injuries, illnesses and improve health among Para athletes. To allow full implementation, the intervention would need to be adapted to the Para athletes´ various impairments, abilities and sports. MAIN QUESTIONS TO BE ADRESSED - Can an evidence-based eHealth health promotion platform prevent sports injuries and illnesses in elite para athletes over 6 months, 12 months and 5 years? - Can such platform improve overall health parameters such as sleep, nutrition and mental health in elite para athletes and influence the performance parameters training quantity and training quality over 6 months, 12 months and 5 years? - Can such platform improve health literacy among Para athletes?

NCT ID: NCT05260515 Not yet recruiting - Clinical trials for Mild Cognitive Impairment

Protecting Alzheimer Caregivers Using Technology Through Staying Sharp

PROACTS
Start date: April 30, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

PROACTS is a Phase I/II study to assess the efficacy of AARP Staying Sharp online health program, focusing on the health of non-professional home-based caregivers of persons with Alzheimer's disease and related dementias (ADRD). PROACTS has three aims. Aim 1&2 is an one-time survey study to evaluate the current uptake and utilization of Staying Sharp among caregivers. Aim 3 is a single-group intervention to assess how Staying Sharp may maintain health and function for caregivers of persons with ADRD. Participants will participate in a 4-month program with a 4-month follow-up. Aim 1&2: Characterize caregivers of persons with ADRD using Staying Sharp and evaluate user experiences of Staying Sharp. Aim 3: Establish preliminary efficacy of Staying Sharp program.