Head and Neck Squamous Cell Carcinoma Clinical Trial
Official title:
Immune Response Evaluation to Curative Conventional Therapy of Stage III/IV Head and Neck Squamous Cell Carcinoma Patients
The IRECT trial is a non-interventional, prospective clinical trial using modern immune
monitoring techniques over the course of the standard of care for HNSCC. The dynamics of
host/tumor immune interactions during the conventional standard treatment will be analyzed to
find the most promising target antigen and to develop a strategy how and when specific
immunotherapy should be added to the current treatment schedule.
The results from this trial will help to understand how state of the art treatment can be
complemented using cancer-testis antigen specific vaccines and immune-modulating drugs to
improve the outcome of head and neck cancer patients.
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