Head and Neck Neoplasms Clinical Trial
Official title:
Remote Ischemic Preconditioning in Head and Neck Cancer Reconstruction - A Randomized Controlled Trial
The purpose of the trial is to investigate, if remote ischemic preconditioning reduces the
risk of complications in patients undergoing resection of head and neck cancer and immediate
reconstruction with autologous free tissue transfer.
Remote ischemic preconditioning is a treatment, which is carried out by inducing brief
episodes of upper arm occlusion using an inflatable tourniquet.
Blood samples will be taken during the operation and postoperatively to evaluate the effects
of remote ischemic preconditioning. These blood samples will be analyzed for clotting
properties and markers of inflammation.
Furthermore, effects on the blood supply of the transferred tissue flap will be measured by
infrared thermography.
Effects on surgical complication rates will be obtained by clinical follow-up and patient
chart review.
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