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Stereotactic Ablative Radiotherapy for Oligo-Progressive Disease REfractory to Systemic Therapy in Metastatic Cancer — SUPPRESS  

Head and Neck Cancer Clinical Trial

Official title:
Stereotactic Ablative Radiotherapy for Oligo-Progressive Disease REfractory to Systemic Therapy in Metastatic Cancer: A Phase II Randomized Trial

Clinical Trial Summary

A registry-based randomized phase II trial. A total of 46 patients with metastatic head and neck cancer on systemic therapy with oligoprogression to 1-5 extracranial lesions will be randomized using a 1:1 ratio to standard of care (begin next-line systemic therapy, best supportive care, continue current systemic line, based on treating physician decision) vs. receive stereotactic ablative radiotherapy to all oligoprogressive lesions while continuing their current systemic therapy.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04989725
Study type Interventional
Source Centre hospitalier de l'Université de Montréal (CHUM)
Contact Silvine Benth
Phone 514-890-8254
Email silvine.benth.chum@ssss.gouv.qc.ca
Status Recruiting
Phase Phase 2
Start date October 1, 2021
Completion date December 1, 2027
View Details
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