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Growth clinical trials

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NCT ID: NCT04316221 Active, not recruiting - Growth Clinical Trials

Effects of Complementary Feeding of Eggs on Infant Development and Growth in Guatemala: The Saqmolo Study

Saqmolo
Start date: April 1, 2021
Phase: N/A
Study type: Interventional

The specific aims of this study are: In a randomized controlled trial, the investigators will evaluate the impact of daily egg consumption during the complementary feeding period in addition to the local standard of nutrition care (i.e., intervention group), compared to the local standard of nutrition care alone (i.e., control group) on the following outcomes, in infants that are ~6-month old at baseline: 1. Child development, as measured by global development scores (primary outcome) 2. Growth, as measured by anthropometrics (secondary outcome) 3. Diet quality, as measured by the World Health Organization infant and young child feeding indicators (secondary outcome) Hypothesis: The investigators hypothesize that daily consumption of eggs during the complementary feeding period, in addition to the local standard of nutrition care, will improve child development, growth, and diet quality compared to the local standard of care alone.

NCT ID: NCT04302987 Completed - Infection Clinical Trials

Vitamin D Intervention in Infants - 6 Years Follow-up (VIDI2)

VIDI2
Start date: November 1, 2019
Phase:
Study type: Observational

Exposure to vitamin D intervention in early life may have permanent effects on physiology and metabolism. Bone growth and mineralization, development of immunity, body composition and brain structure and functioning may be affected. The importance of a long-term surveillance includes follow-up of both beneficial but also harmful effects of vitamin D. Vitamin D intervention in infants (VIDI) study was conducted in 2013-2016. VIDI study was a large randomized trial that aimed to evaluate effects of two vitamin D supplemental doses of daily 10 ug and 30 ug from the age 2 weeks until 2 years on bone strength, infections, immunity, allergy, atopy and asthma, neurologic and cognitive development, and genetic regulation of mineral homeostasis. Current study is a 6 Years Follow-up (VIDI2) study of the original VIDI trial. Our focuses of interest in the follow-up are: bone strength, growth pattern, body composition, and morbidity due to infections and allergic diseases, and the development of immunity. Further, in addition to more classical associates of vitamin D, our aim is to continue to follow-up children's neurocognitive development and mental health. We will also focus on the effect of vitamin D supplementation on occurrence of molar-incisor hypomineralization, dental caries, and oral immunity.

NCT ID: NCT04283799 Completed - Preterm Infant Clinical Trials

Using a New Human Milk Fortifier to Optimize Feeding

Start date: March 16, 2020
Phase: N/A
Study type: Interventional

This study aims to compare the safety and efficacy of a new HMF and those of other HMF used before in very preterm infants.

NCT ID: NCT04281563 Completed - Growth Clinical Trials

Medium-chain Triglyceride Oil Massage on Growth in Preterm

Start date: July 7, 2017
Phase: N/A
Study type: Interventional

Aim: To explore the effect of medium-chain triglyceride (MCT) oil massage on growth in preterm infants. Methods: This randomized controlled trial was conducted in the newborn center of a regional hospital in Taiwan. Preterm infants weighing between 1500 and 2000 g were recruited and randomly assigned to three groups: the MCT oil massage, massage alone and no massage groups. The massages were given three times per day for 7 consecutive days. Weight, length and head circumference were measured in the three groups at birth and on study days 1 to 7.

NCT ID: NCT04213456 Active, not recruiting - Growth Clinical Trials

Double Blind, Randomized, Placebo Controlled Pilot Study to Evaluate the Effect of Nutritional Supplementation on Physical Activity Performance of Young Soccer Players

Start date: February 3, 2020
Phase: N/A
Study type: Interventional

Research has clearly shown that lacking sufficient calories, macro- and micro-nutrients may impair an athlete's training adaptations, while athletes who consume a balanced diet that meets energy needs can enhance physiological training adaptations. Maintaining an energy and nutrient deficient diet during training may lead to loss of muscle mass, strength, and bone mineral density, in addition to an increased susceptibility to illness and injuries, disturbances in immune, endocrine and reproductive function, and an increased prevalence of overreaching and/or overtraining. In children and adolescent athletes, an insufficient diet may additionally result in impaired physical growth. Incorporating good dietary practices as part of a training program is one way to help optimize training adaptations and prevent overtraining. Based on this, nutritional supplementation is an effective and safe approach for attaining the high nutritional requirements of adolescent athletes, to help them maintain healthy growth. Nutritional supplementation could also improve their body composition, sport performance and general health. The primary objective of the proposed study is to evaluate the effect of dietary supplement versus placebo on growth and physical activity performance in young athletes. A total of 50 young soccer players (25 in each group) will participate in this Double blind, randomized, placebo controlled study.

NCT ID: NCT04143204 Completed - Growth Clinical Trials

Nutrition and Growth in Very Preterm Infants

Start date: August 1, 2019
Phase:
Study type: Observational

This study aims to explore the relation of early nutritional intake, especially oral nutrition intake, with growth and body composition among very preterm or very low birth weight infants.

NCT ID: NCT04055363 Completed - Growth Clinical Trials

Human Milk Oligosaccharides (HMOs) Post-market Study on Infants

NEHMO
Start date: October 1, 2018
Phase: N/A
Study type: Interventional

Human milk oligosaccharides (HMOs) represent the third largest solid component of breast milk. Technology advancements made it possible to supplement infant formulas with HMOs (2'FL, LNnT). Two published RCTs have demonstrated that infant formulas supplemented with 2'FL or 2'FL+LNnT are safe, well-tolerated, support normal grow, and may support healthy GI function and confer immune benefits. The performance of HMOs-supplemented formulas assessed in a real-world setting is complementary to previously conducted RCTs conducted in highly controlled clinical settings. Main objectives will be to monitor the safety & tolerance of HMOs-supplemented formulas in larger and diverse infant populations; to assess the performance of HMOs-supplemented formulas in mixed-fed infants, a population that was not studied in previous RCTs but likely represents a relatively common feeding regimen. Finally, considering the potential health/immune benefits of HMOs, it is also important explore the incidences of illnesses (i.e., respiratory illnesses, GI illnesses, and fever) associated with consuming HMOs-supplemented formulas and compare with breastfed infants data.

NCT ID: NCT03996304 Active, not recruiting - Overweight Clinical Trials

Health and Early Life Microbiota

HELMi
Start date: February 26, 2016
Phase:
Study type: Observational

The aim of this cohort is to identify environmental, lifestyle and genetic factors that modify the human intestinal microbiota development during the first years of life, and to identify early microbiota features that associate to child health and well-being with focus on the development of allergic diseases and overweight.

NCT ID: NCT03693287 Recruiting - Growth Clinical Trials

Personalized vs Standardized PN for Preterm Infants >1250g

Start date: July 4, 2021
Phase: Phase 4
Study type: Interventional

Preterm infants (gestational age between 189 and 258 days) with a birth weight (BW) greater than 1250 grams will be randomized to personalized-parenteral nutrition (P-PN) or standardized-parenteral nutrition (S-PN). The aim of the study is to evaluate the effect of S-PN versus P-PN on growth of preterm infants with BW>1250 grams.

NCT ID: NCT03653754 Completed - Child Development Clinical Trials

Growth and Body Composition in Children

Start date: April 16, 2018
Phase:
Study type: Observational

This study is planned to measure and compare body composition indexes and growth between typically developing children and those with disabilities in South Korea for understanding the nutritional and growth status.