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Growth Disorders clinical trials

View clinical trials related to Growth Disorders.

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NCT ID: NCT06329388 Completed - Child Development Clinical Trials

Evaluating the Effects of an Oral Protein Supplement on Children's Growth Patterns

Start date: January 18, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

This single-center, randomized controlled pilot study aims to evaluate the efficacy of TruHeight Growth Protein Shake on improving growth patterns in children aged 4-17 years. Over six months, participants will consume the protein shake daily, five times a week, with outcomes measured in terms of type X collagen concentration in urine, height via a stadiometer, and body composition using an INBODY device.

NCT ID: NCT05889819 Completed - Clinical trials for Nutritional Stunting

Orange Almond Potato Cookies Supplementation

CS
Start date: January 5, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to assess the effect of potato almond orange cookie supplementation on the nutritional status of stunted under-five children. The main questions aimed to answer are: - Can cookie supplementation improve the weight of stunted under-five children? - Can cookie supplementation improve the weight for age z score of stunted under-five children? Participants divided in the two groups i.e.: - Treatment group received 50 g potato almond orange cookie each day during 4 weeks. - Control group received 50 g potato orange cookie each day during 4 weeks. - Mothers of both groups given balanced nutrition education for stunted under-five children twice at the second and third week of study.

NCT ID: NCT05643274 Completed - Neurologic Disorder Clinical Trials

Use of Long Read Genome Sequencing in Patients Suffering From Neurodevelopmental Troubles

HiFi-NDD
Start date: December 19, 2022
Phase:
Study type: Observational

Patients with neurodevelopmental diseases and their families need to identify the genetic cause of the disease to allow for recognition of the disability, genetic counseling, and possible hope for participation in therapeutic research studies. Access to high-throughput genomic exome or genome analysis allows the identification of a genetic cause for approximately half of the patients. However, families with no result or with a variant of unknown significance after these tests may find themselves in a new diagnostic impasse. The high-throughput sequencing used today generates sequences of the order of 100 base pairs (so-called "short read" sequencing). This allows an analysis of about 90% of the genome. However, many regions are not accessible in regions of interest for the genetic diagnosis of rare diseases. Long fragment sequencing generates sequences that are about 20 times larger and its use has recently made it possible to sequence the human genome almost completely (https://www.science.org/doi/10.1126/science.abj6987). The main contribution lies in the analysis of complex regions of the genome such as segmental duplications or centromeric regions. It is likely that this technology increases the sensitivity of detection of genetic variants in patients with genetic diseases. Its contribution should be studied in patients for whom no genetic cause has been identified by classical techniques. This study aim to investigate the contribution of long fragment genome sequencing.

NCT ID: NCT05502978 Completed - Clinical trials for Nutritional Stunting

Education Using WhatsApp and Face-to-Face Meetings on IYCF for the Nutritional Status of Infants

Start date: October 7, 2022
Phase: N/A
Study type: Interventional

The COVID-19 pandemic affects all activities, including stunting prevention. Almost all cities implement Internet-based learning can be used as an alternative to providing education and allows to exchange personal experiences and also establish interpersonal relationships. Education is one of the intervention efforts that aims to foster and improve the health status of the community, while counselling is a technical part of the educational process itself. blended counselling is the integration of online and offline counselling. Blended counselling is a strategy in the covid-19 pandemic condition and after pandemic. the virtual Education method has also been widely used around the world. The WhatsApp application ranks 2 among the most popular social media in Indonesia. Blended education innovations are offered online in the form of digital booklets, videos, online discussions, and online consultations carried out via WhatsApp and offline visits according to health protocols. This blended education is expected to facilitate the work of cadres in providing Infant and young child feeding (IYCF) education, to improve IYCF practices for infant nutritional status.

NCT ID: NCT05448287 Completed - Feeding Behavior Clinical Trials

Suaahara Impact Evaluation: End-line Survey

Start date: June 17, 2022
Phase: Phase 3
Study type: Interventional

Suaahara's primary aim is to reduce the prevalence of stunting, wasting, and underweight among children under 5 years of age and to reduce the prevalence of anemia among women of reproductive age and children 6-59 months of age. For this, the program uses a multi-sectoral approach to achieve four key intermediate results: 1) improved household nutrition, sanitation, and health behaviors; 2) increased use of quality nutrition and health services by women and children; 3) improved access to diverse and nutrient-rich foods by women and children; and 4) accelerated roll-out of the Multi-Sectoral Nutrition Plan (MSNP) through strengthened local governance

NCT ID: NCT05405400 Completed - Depression Clinical Trials

The Sugira Muryango Longitudinal & Spillover Study

Start date: April 20, 2022
Phase:
Study type: Observational

The Early Childhood version of Sugira Muryango is a family-based, home-visiting intervention targeted at early childhood development and implemented with families living in extreme poverty in three districts of Rwanda. This version of Sugira Muryango was first tested in two small pilot studies and a large cluster randomized trial (CRT) was implemented between February 2018 and September 2019 . Pre- to post-intervention findings demonstrated that Sugira Muryango led to improvements in caregiver behaviors linked to child development and health as well as reductions in violence, which were sustained 12 months after the intervention, at which time improvements in child development were observed. The Research Program on Children and Adversity in the Boston College School of Social Work is led by Dr. Theresa S. Betancourt and will, in partnership with the University of Rwanda, FXB-Rwanda and Laterite, conduct a longitudinal follow-up study to investigate the longer-term outcomes of the Sugira Muryango intervention in families who participated in the CRT. The four-year follow-up will examine the long-term and sustained outcomes of the intervention. In particular, the investigators will look at key indicators of long-term positive outcomes for children such as school readiness and transition to formal schooling. Given the lack of longitudinal research on intervention programs supporting ECD in sub-Saharan Africa, this study will contribute greatly to the body of knowledge on the costs and benefits of investments in ECD and guide policy makers and government leaders on making impactful investments in children, leading to long-term benefits for the population at large. The follow-up study involves two activities: Activity A: Pilot to assess measures performance of newly added measures and field test study protocols. Activity B: Four-year follow-up of families who participated in the CRT of the Sugira Muryango intervention.

NCT ID: NCT05244785 Completed - Nutrition, Healthy Clinical Trials

Health and Nutrition Survey on Shenzhen Children

Start date: October 20, 2021
Phase:
Study type: Observational

1. Master and analyze the nutritional health, growth and development status of primary and secondary school students in Shenzhen, and discover the main nutritional health, growth and development problems and influencing factors. 2. Provide basic data and evidence-based basis for the municipal government and related departments to formulate child health policies and measures.

NCT ID: NCT05140928 Completed - Clinical trials for Gastrointestinal Microbiome

The Effect of Maternal Dadiah Supplementation During Pregnancy on Child Growth and Gastrointestinal Health Outcomes

Start date: August 20, 2020
Phase: N/A
Study type: Interventional

The aim of our study is to assess the effect of giving dadiah as a supplement to pregnant women on improving the growth and digestive health of children.

NCT ID: NCT05120427 Completed - Stunting Clinical Trials

The Impact of Growth Charts and Nutritional Supplements on Child Growth in Zambia

ZamCharts
Start date: September 1, 2020
Phase: N/A
Study type: Interventional

According to the latest estimates, 144 million children under age five experience growth faltering. Early life growth faltering or stunting is predictive of a wide array of negative long-term outcomes, including reduced adult height and productivity, diminished health and reduced lifetime incomes. This study builds on a previous pilot study, which suggests that providing parents with tools to measure children's growth at home may be an effective way to prevent early life growth faltering. The objectives of this study are to assess 1) the impact of growth charts on early childhood linear growth; and 2) whether the impact of growth charts can be increased with the provision of food supplements to parents.

NCT ID: NCT05119218 Completed - Stunting Clinical Trials

Gut Microbiota Stunted Children NTT

Start date: November 2, 2021
Phase:
Study type: Observational [Patient Registry]

NTT Province is on the list of priority areas of high prevalence of stunting, Southwest Sumba, South Middle East, and Kupang district have a stunting prevalence of 36.2%, 34.5% and 48.1% respectively in 2020. Therefore, it is necessary to conduct a profile study. microbiota, SCFA, gastrointestinal integrity, parasites, hygiene practice, and cognition in stunting and healthy toddlers in the province of East Nusa Tenggara,