Clinical Trials Logo

Glucose Intolerance clinical trials

View clinical trials related to Glucose Intolerance.

Filter by:
  • Completed  
  • Page 1 ·  Next »

NCT ID: NCT05990205 Completed - PreDiabetes Clinical Trials

Effect of the SCL16A11 Risk Haplotype on Treatments to Prevent Type 2 Diabetes

PRED2
Start date: April 17, 2018
Phase: Phase 2
Study type: Interventional

The goal of this randomized clinical trial is to determine the impact of the risk haplotype on SLC16A11 on early therapeutic responses in treatments to prevent T2D in Mexican mestizos with prediabetes. The main question[s] it aims to answer are: - Evaluate the effect of the risk haplotype on weigth loss >3% - Evualuate the differences in lipid profiles and glycemic parameters (fasting glucose, HbA1c). Participants will be randomized into two groups: lifestyle intervention (LSI): hypocaloric diet, 25 kcal/kg of ideal weight, 45% of the total intake of carbohydrates, 30% lipids, and 25% protein sources + physical activity (>150 min medium intensity per week), or LSI + MET (750 mg metformin twice a day). Researchers will compare carriers and non carriers of the risk haplotype of SLC16A11 to see if there are diferent treatment responses.

NCT ID: NCT05887050 Completed - Glucose Intolerance Clinical Trials

Effects of a Dietary Supplement Containing Salacia Extract, Citrus Bioflavonoids, and Trivalent Chromium on Markers of Glucose Control

Start date: December 3, 2020
Phase: N/A
Study type: Interventional

This study was a double-blind, randomized, placebo-controlled, clinical trial with two parallel groups. Participants reported to a single investigational center in Ohio (i.e., The Center for Applied Health Sciences) during the 12 week trial.

NCT ID: NCT05869344 Completed - PreDiabetes Clinical Trials

Black Bean (Phaseolus Vulgaris L.) Protein Hydrolysates Reduce Acute Postprandial Glucose Levels

Start date: October 15, 2018
Phase: N/A
Study type: Interventional

This work aimed to evaluate the acute effect of a black bean protein hydrolysate (BPH) on glucose levels in adults with normal glucose tolerance (NGT) and prediabetes. Twenty peptides were identified in BPH, and a followed in silico predictive digestion showed a release of several short-chain peptides with potential hypoglycemic potential. A double-blind, placebo-controlled, randomized clinical trial was conducted on 28 adults with NGT or prediabetes. After consent, participants were randomized into two groups, placebo or the corresponding 5 g BPH treatment. An oral glucose tolerance test (OGTT) (75 g glucose) was used to measure glucose tolerance before treatment. A second OGTT was used to evaluate the acute effect of the BPH, and blood samples were collected at 0, 60, 120, and 150 min, and blood glucose levels were measured.

NCT ID: NCT05822648 Completed - Type 2 Diabetes Clinical Trials

Evaluating a Type 2 Diabetes Prevention Program

Start date: April 15, 2023
Phase: N/A
Study type: Interventional

This study aims to test the effectiveness of a Type 2 Diabetes (T2D) prevention program for individuals who have been diagnosed with prediabetes compared to a T2D educational control group. Project health is an obesity prevention program and has produced a 42% to 53% reduction in future onset of overweight/obesity and also produced greater reductions in negative affect compared to assessment-only controls that persisted. Project Health has been adapted to prevent onset of T2D among individuals with prediabetes. The study aims to test the effectiveness of Project Health at reducing BMI, HbA1c levels, increase physical activity and improve glucose control.

NCT ID: NCT05759442 Completed - PreDiabetes Clinical Trials

Clinical Efficacy and Safety of Metformin Versus Apple Cider Vinegar (ACV) in Prediabetics

BUHSCK
Start date: January 1, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare efficacy and safety of metformin versus apple cider vinegar in prediabetics . The main question[s] it aims to answer are: - Efficacy of metformin versus apple cider vinegar in prediabetics - Safety of metformin versus apple cider vinegar in prediabetics Researchers will compare group of prediabetics taking metformin with group of prediabetics taking apple cider vinegar to see if there is difference in safety and efficacy..

NCT ID: NCT05654727 Completed - Clinical trials for Cognitive Impairment

Cognitive Functions and BDNF in T2DM and Prediabetes Patients

Start date: July 1, 2021
Phase:
Study type: Observational

Clinical and epidemiological studies suggest links between cognitive impairments and Type 2 diabetes (T2DM). The underlying mechanisms and causality in diabetes-related cognitive impairment are largely unknown. The aim of this study is to investigate cognitive impairment and the role of BDNF in prediabetes and diabetes patients.

NCT ID: NCT05593926 Completed - Pre-diabetes Clinical Trials

Fibre suppLements fOR Pre-diAbetes - An Assessment Oral Fibre Supplements on Pre-diabetes Outcome Measures

FLORA
Start date: November 16, 2022
Phase: N/A
Study type: Interventional

This trial will investigate whether a powdered fibre mix helps maintain healthy blood glucose levels in participants with pre-diabetes, where high blood sugar is a risk of diabetes.

NCT ID: NCT05560412 Completed - Clinical trials for Overweight and Obesity

Zein Nanoparticles for Glycemic Control

GLUCOCAPS
Start date: January 10, 2023
Phase: N/A
Study type: Interventional

The use of zein nanoparticles as vehicles for drug delivery is under study, but of the effects observed in empty nanoparticles, in laboratory animals, the reduction of glucose levels was something worth studying. Thus, the present research on patients with prediabetes has been proposed. The objective is to assess the efficacy of zein nanoparticles on the glycemic control. For this purpose, a randomized, double blind crossover study has been designed. Target sample size is 60.

NCT ID: NCT05540405 Completed - PreDiabetes Clinical Trials

Effects of Bitter Melon on Cardiometabolic Health

Start date: January 24, 2023
Phase: N/A
Study type: Interventional

The objectives of this study are to assess the effects of a bitter melon product at two doses, compared to control, on indicators of cardiometabolic health among men and women with prediabetes.

NCT ID: NCT05497960 Completed - PreDiabetes Clinical Trials

Vivo Prediabetes Study: Online, Live, and Interactive Strength Training for Older Adults With Prediabetes

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

This research trial studies the effect of an online, live and interactive strength training program on physical function and strength in older adults with prediabetes.