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Glaucoma clinical trials

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NCT ID: NCT04947124 Completed - Glaucoma Clinical Trials

A Study to Determine the Safety and Tolerability of 2 Concentrations of QLS-101

Start date: October 19, 2021
Phase: Phase 2
Study type: Interventional

Safety and tolerability study of 2 concentrations of QLS-101 for adult subjects with Sturge Weber Syndrome (SWS)-related glaucoma due to elevated episcleral venous pressure (EVP).

NCT ID: NCT04944290 Completed - Ocular Hypertension Clinical Trials

To Compare the Efficacy and Safety of Perrigo's Product to an FDA Approved Product for the Treatment of Glaucoma or Ocular Hypertension in Both Eyes

Start date: May 28, 2021
Phase: Phase 3
Study type: Interventional

To compare the efficacy and safety of Perrigo's product to an FDA approved product in the treatment of Primary Open Angle Glaucoma or Ocular Hypertension in Both Eyes.

NCT ID: NCT04931290 Completed - Glaucoma Clinical Trials

Supracapsular Ahmed Glaucoma Valve Plate Delivery Technique for Management of Encapsulated Bleb in Pediatric Patients

Start date: April 6, 2021
Phase: N/A
Study type: Interventional

This study aims to assess the safety and efficacy of supracapsular Ahmed Glaucoma Valve plate delivery for management of encapsulated bleb in pediatric patients with failed Ahmed Glaucoma Valve. This is a prospective interventional study. It will be conducted in Mansoura University in the duration from April 2020 to January 2021. The study will include pediatric patients less than 18 years with failed AGV with encapsulated bleb and high IOP above 21 mm Hg in two consecutive visits inspite of topical glaucoma medications

NCT ID: NCT04911387 Completed - Glaucoma Clinical Trials

iCare® Home vs Goldmann Applanation Tonometry

Start date: April 1, 2020
Phase:
Study type: Observational

Self-tonometry with iCare Home is regularly performed at Sankt Erik's Eye Hospital since a few years back. The purpose of this study was to show that the eye pressure measurements made with iCare® Home by patients / relatives do not vary more than those made with the standard method, Goldman applanation tonometry (GAT), by different healthcare professionals. This will hopefully confirm the usefulness of self-tonometry.

NCT ID: NCT04910100 Completed - Ocular Hypertension Clinical Trials

Nebivolol 0.5, 1.0, or Timolol 0.5 Suspension Compared to Timolol 0.5 Solution to Treat Glaucoma/Ocular Hypertension

Start date: April 15, 2021
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety (in the eye and throughout the body) and effectiveness of nebivolol (0.5 and 1 percent) and timolol (0.5 percent) eye drop suspensions. These eye drops will be compared to timolol 0.5 percent eye drop solution in participants with open angle glaucoma (the most common type of glaucoma) or high eye pressure (ocular hypertension).

NCT ID: NCT04890106 Completed - Clinical trials for Glaucoma, Open-Angle

Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% to LUMIGAN® In The Treatment of Chronic Open-Angle Glaucoma

Glaucoma
Start date: October 2, 2021
Phase: Phase 3
Study type: Interventional

This is a randomized, double-masked, two-treatment, single-period, parallel design, multiple dose at multiple clinical trial sites designed to demonstrate bioequivalence with clinical endpoint in subjects with chronic open-angle glaucoma or ocular hypertension in both eyes. Test Product - Bimatoprost Ophthalmic Solution, 0.01% of Mankind Pharma Limited, India Reference Product - LUMIGAN® (Bimatoprost Ophthalmic Solution) 0.01% of Allergan, Inc.,

NCT ID: NCT04888156 Completed - Glaucoma Clinical Trials

Impact of Self-tonometry on Glaucoma Treatment Decision.

Start date: May 10, 2021
Phase:
Study type: Observational

Self-tonometry with iCare Home is performed by one hundred patients annually at Sankt Erik's Eye Hospital. The investigators want to evaluate the impact that self-tonometry results have on the clinician's choice of glaucoma treatment. The investigators also want to evaluate how often pressure peaks occur outside the clinic's opening hours.

NCT ID: NCT04872348 Completed - Clinical trials for Glaucoma, Open-Angle

An Observational Multicenter Clinical Study To Assess The Safety And Effectiveness Of The OMNI® Surgical System In Pseudophakic Eyes With Primary Open Angle Glaucoma (ORION 2.0)

Start date: July 1, 2021
Phase:
Study type: Observational

The purpose of this study is to evaluate the safety and effectiveness of the OMNI® Surgical System in subjects who have undergone canaloplasty and trabeculotomy using OMNI® Surgical System without any concomitant surgery in pseudophakic eyes with mild to moderate primary open angle glaucoma (POAG) at least 150 days prior to enrollment.

NCT ID: NCT04868175 Completed - Glaucoma Clinical Trials

Interval Intraocular Pressure in Intravitreal Injection Study

IIII
Start date: October 1, 2019
Phase: N/A
Study type: Interventional

This is a prospective study of IOP in Intravitreal injections to evaluate: 1. IOP effect of intravitreal injection 2. IOP response to prophylactic beta blocker or Prostaglandin vs control (Hypromellose) over multiple time periods 3. IOP response in correlation to number of injections, IOL, type of anti VEGF, co morbidities

NCT ID: NCT04857827 Completed - Clinical trials for Normal Tension Glaucoma (NTG)

A Study to Evaluate Safety and Tolerability of QLS-101 in NTG

Start date: September 15, 2021
Phase: Phase 2
Study type: Interventional

A randomized active-controlled multi-site double-masked 28 day study to evaluate the safety and tolerability of QLS-101 versus timolol maleate Preservative Free (PF) 0.5% ophthalmic solution in subjects with normal tension glaucoma