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Glaucoma clinical trials

View clinical trials related to Glaucoma.

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NCT ID: NCT05089474 Completed - Open Angle Glaucoma Clinical Trials

A First in Human Clinical Trial to Evaluate the Safety and Effectiveness of the STREAMLINE SURGICAL SYSTEM in Patients With Open-Angle Glaucoma

Start date: March 8, 2021
Phase: N/A
Study type: Interventional

A prospective, nonrandomized, open label study to evaluate the safety and IOP lowering effectiveness of the Streamline Surgical System, in patients with mild-to-moderate open angle glaucoma undergoing cataract surgery.

NCT ID: NCT05080153 Completed - Glaucoma Clinical Trials

Effect of Vitamin Supplementation in Glaucoma Patients

Start date: November 15, 2019
Phase:
Study type: Observational

The impact of targeted vitamin supplementation on retinal venous pressure (RVP) and steady state pattern ERG (SSpERG) in patients with RVP 15mmHg or more above intra-ocular pressure (IOP) and serum homocystein 12µmol/l or more, with signs of progression in spite of adequate IOP control, as evidenced by SSpERG abnormality with or without structural progression or visual field progression,

NCT ID: NCT05044793 Completed - Clinical trials for Glaucoma, Open-Angle

A Clinical Study To Assess The Safety And Effectiveness Of The OMNI® Surgical System

Start date: September 30, 2021
Phase:
Study type: Observational

The purpose of this study is to evaluate the long-term safety and effectiveness of the OMNI® Surgical System in subjects who were treated under protocol #06213

NCT ID: NCT05042609 Completed - Clinical trials for Non-infectious Anterior Uveitis

A Study of TRS01 in Subjects With Active Non-infectious Anterior Uveitis Including Subjects With Uveitic Glaucoma

Start date: September 20, 2021
Phase: Phase 3
Study type: Interventional

The primary objective of this study is to evaluate the efficacy and safety of TRS01 eye drops compared to active comparator in subjects with active non-infectious anterior uveitis with or without uveitic glaucoma

NCT ID: NCT05022004 Completed - Ocular Hypertension Clinical Trials

A Therapeutic Equivalence Study in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension

Start date: December 20, 2021
Phase: Phase 3
Study type: Interventional

This is a randomized, Investigator-masked, multi-center, parallel group, therapeutic equivalence study with clinical endpoint.

NCT ID: NCT04972695 Completed - Glaucoma Clinical Trials

Validation of an Automatic Analysis Algorithm of the Probability of Glaucoma From Optic Disc Images

Start date: May 7, 2021
Phase:
Study type: Observational

Clinical, cross-sectional and prospective study to assess the images of the posterior pole of the retina of patients from the Glaucoma Unit of the IOBA and the Hospital Clínico Universitario de Valladolid during the period between May and December 2021. The aim of the project is to provide a sufficient number of images from posterior pole retinographies in patients with suspected glaucoma or with diagnosis of glaucoma in order to determine the sensitivity and specificity of an automatic glaucoma screening algorithm developed by the company Transmural Biotech S.L.

NCT ID: NCT04972435 Completed - Senile Cataract Clinical Trials

Effect of Multifocal Intraocular Lens on Contrast Sensitivity in Primary Angle-Closure Patients

Start date: January 2, 2014
Phase: N/A
Study type: Interventional

This prospective study included patients with primary angle-closure (PAC or primary angle-closure glaucoma (PACG) and visually significant cataract. Phacoemulsification with multifocal intraocular lens (MIOL) or monofocal IOL (mIOL) (patient preference) was performed. Collected data included best-corrected distant visual acuity (BCVA), intraocular pressure (IOP), anterior chamber depth (ACD), and contrast sensitivity (CS) measured at spatial frequency 1.5, 3.0, 6.0, 12.0, and 18.0 cycles per degree (CPD) preoperatively, and at 2-6 months postoperatively. Preoperative and postoperative parameters were compared to evaluate the effect of MIOL on CS in eyes with PAC or PACG.

NCT ID: NCT04970251 Completed - Clinical trials for Intraocular Pressure

Aflibercept as Adjunctive Treatment for Filtration Surgery in Neovascular Glaucoma

Start date: November 1, 2018
Phase: N/A
Study type: Interventional

Purpose: To investigate intravitreal aflibercept (IVA) injection as an adjunctive treatment to trabeculectomy with mitomycin C (TMC) and panretinal photocoagulation (PRP) for neovascular glaucoma (NVG). Setting: Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand Study design: Prospective interventional case series Methods: PRP and IVA (2 mg/0.05 ml) injection were given, and TMC was performed within 2 weeks after IVA. Additional PRP, laser suture lysis, subconjunctival 5-fluorouracil injection, and bleb needling were performed after TMC if indicated. Best-collected visual acuity (BCVA), intraocular pressure (IOP), surgical complications, and number of anti-glaucoma medications were collected.

NCT ID: NCT04949802 Completed - Glaucoma Clinical Trials

Glaucoma Surgery Using the ViaLase Laser System

Start date: September 1, 2020
Phase: N/A
Study type: Interventional

Prospective, single-center, multi-cohort clinical trial of ViaLase Laser for the reduction of IOP in patients with open angle glaucoma.

NCT ID: NCT04949347 Completed - Glaucoma Clinical Trials

Glycerin-Preserved, Human-Donor, Corneoscleral Patch Grafts for Glaucoma Drainage Devices

Start date: February 22, 2017
Phase:
Study type: Observational

This was a retrospective, non-comparative study of 100 eyes of 100 consecutive glaucoma patients who had undergone glaucoma drainage device implantation (Baerveldt shunt) during January 2006 to December 2016. Glycerin-preserved, human-donor, corneoscleral tissue was used as a patch graft to cover the tube portion of the GDD over the sclera. The patch graft related complication was comparable to the previous reports using conventional sclera or pericardium.