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Glaucoma clinical trials

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NCT ID: NCT06071494 Recruiting - Primary Glaucoma Clinical Trials

The Effect Of Tropical Fruits In Patients With Primary Glaucoma

Start date: February 1, 2024
Phase: N/A
Study type: Interventional

To evaluate the effect of regular tropical fruits intake in primary glaucoma patients. Methodology : Research Design Randomized controlled trial Study Duration February 2024-June 2025 Study Location 1. Ophthalmology Clinic, Hospital Universiti Sains Malaysia, Kelantan Source Reference Population Adults with primary glaucoma in Peninsular Malaysia Study Source Population Adults with primary glaucoma attending Ophthalmology clinic, Hospital Universiti Sains Malaysia during study duration.

NCT ID: NCT06066645 Recruiting - Clinical trials for Glaucoma, Open-Angle

Travoprost Intraocular Implant + iStent Infinite vs. iStent Infinite Alone

Start date: September 14, 2023
Phase: Phase 3
Study type: Interventional

Adult subjects with elevated intraocular pressure who have successfully undergone placement of iStent infinite trabecular bypass system will be randomized to receive a travoprost intraocular implant or receive a sham procedure and be followed for 12 months.

NCT ID: NCT06058598 Recruiting - Clinical trials for Glaucoma, Open-Angle

Exercise Training in Patients With Glaucoma

HIT GLAUCOMA
Start date: December 1, 2023
Phase: N/A
Study type: Interventional

HIT GLAUCOMA is a multicenter exercise study for glaucoma patients between three institutes: the Department of Sport, Exercise and Health (DSBG) of the University of Basel, the Eye Clinic at the University Hospital Basel and the UZ Leuven (Belgium). The main objective of the study is to investigate the possibility of using exercise therapy to treat glaucoma. Participants will be randomly divided into two groups: Intervention and Control group. The intervention group will receive a high-intensity interval training plan, and the control group will receive lifestyle counseling and standard therapy. With this method, the study aims to validate an exercise therapy concept that could significantly improve disease progression and quality of life in patients with glaucoma.

NCT ID: NCT06057051 Recruiting - Glaucoma Clinical Trials

Glaukos® iStent Infinite Trabecular Micro-Bypass System in Subjects With Mild to Moderate Primary Open-angle Glaucoma

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

Prospective, multicenter, single-arm study of the iStent infinite in adult pseudophakic or phakic subjects with mild to moderate primary open angle glaucoma who have not failed conventional medical and surgical treatment

NCT ID: NCT06017362 Recruiting - Glaucoma Clinical Trials

Clinical Trial To Determine The Efficacy And Safety Of Insulin Eye Drops In Dry Eye In Patients With Topical Hypotensors

Start date: February 8, 2023
Phase: Phase 4
Study type: Interventional

The goal of this clinical trial is to evaluate the preliminary efficacy of the use of insulin eye drops in the control of dry eye disease in patients with topical hypotensors, compared to placebo (artificial tears). The main question aims to answer whether glaucoma patients treated with topical hypotensors could benefit from the use of insulin eye drops for the treatment of dry eye. Participants will be assigned to one of the two treatment arms and will be required to attend four follow-up visits (baseline, 1, 3, and 6 months).

NCT ID: NCT06016972 Recruiting - Clinical trials for Primary Open Angle Glaucoma (POAG)

Qlaris Phase 2 Study of QLS-111 in POAG and/or OHT Patients

Start date: March 15, 2024
Phase: Phase 2
Study type: Interventional

Qlaris' Phase 2 clinical trial investigating the safety, tolerability, and ocular hypotensive efficacy of QLS-111 in primary open-angle glaucoma (POAG) or ocular hypertension patients.

NCT ID: NCT06012058 Recruiting - Glaucoma Clinical Trials

Glaucoma Screening With Artificial Intelligence

Start date: August 26, 2023
Phase: N/A
Study type: Interventional

This randomized clinical trial aims to compare the diagnostic performance of two AI-enabled screening strategies - ROTA (RNFL optical texture analysis) assessment versus optic disc photography - in detecting glaucoma within a population-based sample. Secondary objectives are to (1) compare the diagnostic performance of ROTA AI assessment versus OCT RNFL thickness assessment by AI, and ROTA AI assessment versus OCT RNFL thickness assessment by trained graders, (2) investigate the cost-effectiveness of AI ROTA assessment for glaucoma screening, and (3) estimate the prevalence of glaucoma in Hong Kong.

NCT ID: NCT06000865 Recruiting - Glaucoma Clinical Trials

Glaucoma Rehabilitation With Action viDeo Games and Exercise - GRADE

Start date: September 9, 2023
Phase: N/A
Study type: Interventional

Falls are one of the most serious public health concerns for seniors, with significant medical and economic consequences. This concern is even higher in patients with peripheral field loss due to glaucoma because of the patients' compromised visual input. The investigators' project proposes an innovative, entertaining, easily accessible and enjoyable intervention for improving mobility and postural control function in glaucoma patients with peripheral vision loss, who are more prone to falls and suffer from fear of falling. The new intervention examined in this project can be implemented in current vision and balance rehabilitation programs, and may benefit patients with different types of visual impairment to minimize their risk of falls and improve their quality of life.

NCT ID: NCT05999006 Recruiting - Clinical trials for Glaucoma, Primary Open Angle

Safety and Feasibility of the ELIOS System in POAG Patients

Start date: October 18, 2023
Phase: N/A
Study type: Interventional

Evaluation of the safety and effectiveness of the ELIOS System procedure to reduce intraocular pressure (IOP) in adult subjects with mild to moderate primary open-angle glaucoma (POAG)

NCT ID: NCT05954637 Recruiting - Glaucoma Clinical Trials

Correlation of Structure and Function in Glaucoma

Start date: July 1, 2023
Phase:
Study type: Observational

The aim of the study is to correlate structure and function in patients with glaucoma. To this end, a cross-sectional study unsing perimetry and optical coherence tomography is performed.