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Glaucoma clinical trials

View clinical trials related to Glaucoma.

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NCT ID: NCT00485238 Recruiting - Glaucoma Clinical Trials

ALPI vs Medical Therapy Effects on Optic Nerve Structure & Function

Iridoplasty
Start date: February 2007
Phase: Phase 4
Study type: Interventional

The aim is to determine which approach, immediate argon laser peripheral iridoplasty or conventional systemic medical treatment efficiently breaks acute angle closure attack without consequent visual morbidities. The specific objectives are to see whether sudden intraocular pressure(IOP) lowering brought about by laser iridoplasty or medical treatment affects optic nerve head structure and function and identify if immediate decompression is associated with greater incidence of ocular problems like corneal endothelial compromise, optic disc edema, macular edema, decompression retinopathy, cataract formation, progression to chronic angle closure.

NCT ID: NCT00481494 Recruiting - Glaucoma Clinical Trials

Personality Characteristics and Compliance With Antiglaucoma Medication

GDC
Start date: May 2007
Phase: N/A
Study type: Observational

Personality traits may influence to the drug compliance in glaucoma patients.

NCT ID: NCT00478790 Recruiting - Pterygium Clinical Trials

Ologen(Oculusgen)-Glaucoma and Pterygium Historical Control Study in China Shanghai Sixth People's Hospital

Start date: February 2007
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether the ologen (OculusGen) Collagen Matrix are effective and safe to implant as an aid of glaucoma surgery and pterygium excision surgery.

NCT ID: NCT00468429 Recruiting - Glaucoma Clinical Trials

Subconjunctival Bevacizumab to Prevent Bleb Failure After Glaucoma Filtration Surgery

Start date: May 2007
Phase: Phase 4
Study type: Interventional

This study analyzes the safety and efficacy of off-label Subconjunctival Injection of bevacizumab (Avastin) versus 0.02% mitomycin C (MMC) for preventing bleb failure following glaucoma filtration surgery.

NCT ID: NCT00453024 Recruiting - Advanced Glaucoma Clinical Trials

Imaging Ahmed Glaucoma Tubes With a Pericardial Graft and Tissue Glue or Partial-Thickness Scleral Flap and Sutures

Start date: February 2007
Phase: Phase 2
Study type: Interventional

When implanting an Ahmed glaucoma tube, a scleral flap is usually created to cover the tube, and the conjunctiva is stitched back in place with nylon 10-0 sutures. It is hypothesized that an equally safe or better method is using a bovine pericardial patch graft that can be secured in place over the tube with tissue glue, and using tissue glue to reposition the conjunctiva in place.

NCT ID: NCT00449098 Recruiting - Glaucoma Clinical Trials

Ologen (OculusGen)-Glaucoma MMC Control Trial in India

Start date: January 2007
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare the safety and effectiveness of the ologen (OculusGen) Biodegradable Collagen Matrix Implant and the MMC group in filtration surgery.

NCT ID: NCT00443664 Recruiting - Clinical trials for Primary Open Angle Glaucoma

External Micropulse Diode Laser Transscleral Trabeculoplasty (EMDLT) for Severe Open Angle Glaucoma

EMDLT
Start date: June 2006
Phase: Phase 0
Study type: Interventional

To prove that external contact micropulse diode laser trabeculoplasty (EMDLT) can significantly lower intraocular pressure in cases of advanced open angle glaucoma.

NCT ID: NCT00440336 Recruiting - Open Angle Glaucoma Clinical Trials

Comparison of Efficacy of Two Groups of Glaucoma Drops (Xalatan vs.Cosopt) in Reducing Eye Pressure Following Laser (SLT)Treatment in the Management of Glaucoma.

Start date: October 2006
Phase: N/A
Study type: Interventional

WHAT IS THIS STUDY ABOUT? Glaucoma and ocular hypertension are chronic eye diseases that can damage the optic nerve and lead to vision loss or blindness. The optic nerve acts like an electric cable with over a million wires. This nerve is responsible for carrying images from the eye to the brain. The way glaucoma and ocular hypertension cause blindness depends on many factors, but the most important factor is the increased pressure inside the eye (intraocular pressure). There is no cure for glaucoma or ocular hypertension. However, lowering the pressure inside the eye has been shown to slow the progression of disease. Intraocular pressure can be lowered by glaucoma medication, laser treatment, or surgery. You have open angle glaucoma, pseudoexfoliative glaucoma, or ocular hypertension. Researchers want to find out more about how 2 drugs called Cosopt (dorzolamide hydrochloride and timolol maleate) and Xalatan (latanoprost) can help people with these conditions. Cosopt and Xalatan are both eye drops that are approved by the U.S. Food and Drug Administration (FDA) to reduce intraocular pressure in people with open angle glaucoma and ocular hypertension. The study doctor will do a laser procedure called Selective Laser Trabeculoplasty (SLT) on people in this study to help lower their intraocular pressure. The FDA has approved SLT to treat open angle glaucoma and ocular hypertension. Then the study doctor will ask some participants to use either Cosopt or Xalatan, if their intraocular pressure is still too high 4 to 6 weeks after the SLT procedure. The study doctor wants to see which of the 2 study drugs (Cosopt or Xalatan) is better at reducing intraocular pressure after SLT. It is planned that about 30 people with glaucoma or ocular hypertension who are at least 18 years old will be in this study. Out of the participants whose intraocular pressure is still too high after SLT, half will use Cosopt and half will use Xalatan. You do not have to be in this study to have SLT or to use Cosopt or Xalatan.

NCT ID: NCT00409669 Recruiting - Clinical trials for Elevated Intraocular Pressure

Intraocular Pressure Accuracy and Variability of the Barraquer Tonometer

Start date: November 2006
Phase: N/A
Study type: Interventional

To determine if the Barraquer tonometer provides an accurate and reliable measurement of intraocular pressure. The Barraquer tonometer is a device used to safely and painlessly measure intraocular pressure.

NCT ID: NCT00349414 Recruiting - Refractory Glaucoma Clinical Trials

Safety Study of Conventional Versus Micropulse Transscleral Cyclophotocoagulation in Treating End-Stage Glaucoma

Start date: July 2006
Phase: Phase 1/Phase 2
Study type: Interventional

The aim of this study is to compare the safety and efficacy of conventional and micropulse transscleral diode laser in the treatment of end-stage glaucoma.