Gestational Diabetes Clinical Trial
Official title:
Evidence-informed Trial of Lifestyle Interventions to Improve Glycemic Parameters and Reduce Gestational Diabetes in High-risk Pregnant Individuals
The goal of this study is assess the impact of a higher intensity dietary and activity counseling program to improve blood sugar control and reduce the chance of developing gestational diabetes (GDM) as compared to the current standard diet and activity counseling.
GDM is associated with adverse maternal and newborn outcomes, as well as potential lifelong consequences. Currently, clinical guidelines recommend screening for pre-existing Type 2 diabetes mellitus at new obstetric visits for individuals at high risk of developing GDM. For those who do not screen positive, but still may be at risk for GDM, standard practice is for basic diet, exercise, and weight gain counseling. In this study, eligible participants will be randomized into one of two groups: usual care with standard diet and exercise counseling or a GDM prevention program that consists of a more intensive exercise and monitoring program. All participants will be asked to wear an activity tracker and continuous glucose monitors (CGMs) at specified time points throughout their pregnancy. Blood will be drawn at specified time points to measure hemoglobin A1c, lipids, and HOMA-IR measures. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05081037 -
Integrated Hyperglycaemia Incentivised Postnatal Surveillance Study (I-HIPS)
|
N/A | |
| Active, not recruiting |
NCT03249896 -
Web/Smartphone-based Lifestyle Coaching Program in Pregnant Women With Gestational Diabetes
|
N/A | |
| Terminated |
NCT03749889 -
Low Carb vs Normal Carb in Pregnancy
|
N/A | |
| Completed |
NCT03859193 -
Education Nutritional Video for Gestational Diabetics
|
N/A | |
| Recruiting |
NCT05037526 -
Utility of Real Time Continuous Glucose Monitoring in the Care of Gestational Diabetes Versus Standard Care in Pregnancy Outcomes
|
N/A | |
| Completed |
NCT06178250 -
Placenta, Fetal Liver, Sectional Ductus Venosus Volumes Examined by Three-dimensional Ultrasound in the Second Trimester
|
N/A | |
| Not yet recruiting |
NCT06310356 -
Continuous Glucose Monitoring for Women With Gestational Diabetes
|
N/A | |
| Not yet recruiting |
NCT06445530 -
Nutrition Optimization and Community Upliftment for Postpartum Recovery
|
N/A | |
| Recruiting |
NCT02590016 -
Glucose Control During Labour in Gestational Diabetes Mellitus With Insulin Treatment: A Randomized Controlled Trial
|
Phase 4 | |
| Not yet recruiting |
NCT00883259 -
Metformin and Gestational Diabetes in High-risk Patients: a RCTs
|
Phase 4 | |
| Withdrawn |
NCT01947699 -
Glycemic Profile in Women With Gestational Diabetes Treated With Glyburide
|
Phase 4 | |
| Recruiting |
NCT03008824 -
Micronutrients in Pregnancy as a Risk Factor for Diabetes and Effects on Mother and Baby
|
N/A | |
| Active, not recruiting |
NCT01340924 -
Relationship Between Gestational Diabetes and Type 2 Diabetes
|
||
| Completed |
NCT00534105 -
Lipid Metabolism in Gestational Diabetes
|
N/A | |
| Recruiting |
NCT00371306 -
Comparison of Glucovance to Insulin for Diabetes During Pregnancy
|
N/A | |
| Completed |
NCT03388723 -
Intergenerational Programming of Diabesity in Offspring of Women With Gestational Diabetes Mellitus
|
||
| Recruiting |
NCT04521712 -
Postpartum Glycemia in Women at Risk For Persistent Hyperglycemia
|
N/A | |
| Enrolling by invitation |
NCT03307486 -
Gestational Diabetes: a Cohort Study
|
N/A | |
| Active, not recruiting |
NCT03301792 -
Group Versus Traditional Prenatal Care for Diabetes
|
N/A | |
| Enrolling by invitation |
NCT05603793 -
YoUng Adolescents' behaViour, musculoskeletAl heAlth, Growth & Nutrition
|