A Pragmatic Approach to Lowering the Risk of Diabetes Mellitus After A

Status Recruiting

Clinical Trial Summary

A Pilot of Metformin Postpartum

Clinical Trial Description

The overall goal of this proposal is to assess metformin initiation at the time of hospital discharge for women with a history of gestational diabetes mellitus (GDM) improves maternal health at 1 year post-partum. Our central hypothesis is that diabetes mellitus (DM) prevention with metformin can be initiated days after delivery, rather than months to years after delivery, and result in a pragmatic and efficacious means of preventing DM and improving weight loss over the first year post-partum. To test this hypothesis, we will perform a open-label randomized controlled trial of metformin compared to placebo routine care initiated at the time of hospital discharge in women with a history of GDM. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04615351
Study type	Interventional
Source	Women and Infants Hospital of Rhode Island
Contact	Donna Allard
Phone	4012741122
Email	dallard@wihri.org
Status	Recruiting
Phase	Phase 3
Start date	November 15, 2020
Completion date	June 30, 2022

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A Pragmatic Approach to Lowering the Risk of Diabetes Mellitus After A Diagnosis of Gestational Diabetes Mellitus

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms