Periodontitis Clinical Trial
Official title:
A Study on the Oral Health Status of Pregnant Women With Gestational Diabetes (GDM) and Its Correlation With Oral Flora
The aim of this observational study was to find out the oral status of pregnant women with GDM. The main questions it aims to answer are. - What is the oral status of pregnant women with GDM - Does GDM cause changes in the patient's oral flora Participants will describe the main tasks that participants will be asked to complete. The researcher will compare the [periodontal health group] to see if there is [different flora].
1. A self-administered general questionnaire, a semi-quantitative food frequency questionnaire, an oral health self-efficacy scale, an oral health literacy scale, and an oral health assessment scale were used for data collection to understand the current status of periodontitis in pregnant women with GDM, and to analyze the effects of demographic characteristics, dietary patterns, psychological factors and oral health-related knowledge on them; and biochemical indexes, such as fasting glucose, glycated hemoglobin, etc., and the outcome of pregnancy were collected in the late stage of pregnancy in pregnant women with GDM, so as to explore the effect of the current status of periodontitis in pregnant women with GDM on the outcome of their pregnancy. 2. Forty cases of GDM pregnant women in the periodontal health group and 40 cases in the periodontitis group were randomly selected, and the saliva specimens of GDM pregnant women in the periodontal health group and GDM pregnant women in the periodontitis group were collected. Saliva specimens from GDM pregnant women in the healthy group and GDM pregnant women in the periodontitis group were collected in the late pregnancy period, and the oral flora was detected by 16S rRNA high-throughput sequencing technology, so as to compare the differences in the distribution of oral flora between the two groups and to analyze the correlation between oral flora and periodontitis among GDM pregnant women. flora of GDM pregnant women and its correlation with periodontitis. ;
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