Early Diagnosis of GDM by Multiomics

Status Recruiting

Clinical Trial Summary

Gestational diabetes mellitus (GDM) is prone to cause a variety of adverse pregnancy outcomes, and has potential harm to the short-term and long-term health of both mothers and infants. However, its diagnosis mainly relies on oral glucose tolerance test (OGTT) at 24-28 weeks of gestation, so it is often diagnosed in the second and third trimester, and may be too late to intervene. Therefore, advancing the diagnostic window period of GDM is the key to the prevention and treatment of GDM and its complications. It is urgent to establish a new technology for the early diagnosis and screening of GDM with high detection rate and accuracy. Based on literature survey and previous studies, this study found that the combined analysis of metabolomics and lipidomics may have broad clinical application prospects in the early diagnosis and screening of GDM. It is hoped that a set of new techniques based on multi-omics for early diagnosis and screening of GDM can be constructed, providing a feasible and effective tool for early detection and treatment of GDM in clinical.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05386927
Study type	Observational
Source	Women's Hospital School Of Medicine Zhejiang University
Contact	Zhaoxia Liang, Prof.
Phone	86571-89992115
Email	xiaozaizai@zju.edu.cn
Status	Recruiting
Phase
Start date	May 1, 2022
Completion date	December 31, 2024

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT06099574` - A Study on the Oral Health Status of Pregnant Women With Gestational Diabetes and Its Correlation With Oral Flora
Completed	`NCT02744300` - Balance After Baby Intervention for Women With Recent Gestational Diabetes	N/A
Completed	`NCT02890693` - Improving Cardio-metabolic and Mental Health in Women With Gestational Diabetes Mellitus and Their Offspring	N/A
Completed	`NCT02436551` - Gestational Diabetes in Central Asia: Prevalence and Management
Completed	`NCT02384226` - User Testing and Feedback for a Mobile Health Program for Postpartum Women: A Pilot Study
Recruiting	`NCT02275845` - Medico-GDM Trial - Metformine to Prevent Gestational Diabetes Mellitus	Phase 3
Recruiting	`NCT04621396` - The Next Generation Longitudinal Birth Cohort Diabetes Study
Completed	`NCT01931280` - A Transgenerational e-Intervention for Gestational Diabetics and Their Offspring	N/A
Completed	`NCT01916694` - Trial of Remote Evaluation and Treatment of Gestational Diabetes Mellitus	N/A
Not yet recruiting	`NCT01637727` - Long Term Effects of Gestational Diabetes Mellitus in a Population of Parous Women	N/A
Completed	`NCT01565564` - Randomized Translational Study to Examine the Effects of Shared Care in Management of Gestational Diabetes	N/A
Recruiting	`NCT00550979` - Gestational Diabetes Mellitus and Implications for Cardiovascular Disease Risk	N/A
Completed	`NCT00460018` - Diet, Exercise, and Breastfeeding Intervention Program for Women With Gestational Diabetes (DEBI Trial)	Phase 2
Not yet recruiting	`NCT04915716` - Effect of Fasting Time Before Cesarean Section on Neonatal Blood Glucose in Pregnant Women With Gestational Diabetes Mellitus
Completed	`NCT04422821` - Flash Glucose Monitoring in Gestational Diabetes Mellitus: Study Protocol for a Randomized Controlled Trial	N/A
Recruiting	`NCT04369313` - Effect of DCC on Neonatal Jaundice and Blood Gas Analysis in Infants Born to GDM Mothers	N/A
Recruiting	`NCT05348863` - SPARK- a Digital Platform to Improve Self-management of Gestational Diabetes	N/A
Recruiting	`NCT04272840` - The Impact of Glycemic Index Education on Lowering Dietary GI in Gestational Diabetes Mellitus	N/A
Completed	`NCT02588729` - A Mobile Smartphone Application to Promote a Healthy Diet and Physical Activity Among Pregnant Women With GDM - RCT	N/A
Completed	`NCT01922791` - Nutrition and Pregnancy Intervention Study	N/A