Clinical Trials Logo

General Anesthesia clinical trials

View clinical trials related to General Anesthesia.

Filter by:

NCT ID: NCT03058263 Completed - General Anesthesia Clinical Trials

Effect of Neostigmine on the Recovery of Rocuronium: A Comparison Between Partial and TOF Ratio-Based Dose

Start date: October 2016
Phase: Phase 1/Phase 2
Study type: Interventional

This study aimed to evaluate the effect of Neostigmine partial dose towards neuromuscular blockade of rocuronium

NCT ID: NCT03019354 Recruiting - General Anesthesia Clinical Trials

The Effect of Using High-flow Nasal Oxygen-delivery System in Patients Under Intravenous General Anesthesia

Start date: January 2017
Phase: N/A
Study type: Interventional

In general anesthesia, gas exchange was altered by shunt and uneven ventilation perfusion ratios. Lung atelectasis was a cause of impaired oxygenation. High-flow nasal cannula oxygen therapy delivers adequately heated and humidified medical gas at up to 60 L/min of flow. It has physiological effects: reduction of anatomical dead space, positive end expiratory pressure (PEEP) effect, constant fraction of inspired oxygen, and good humidification. The hypothesis of this study is using high-flow nasal oxygen in intravenous general anesthesia could improve lung function and prevent lung atelectasis.

NCT ID: NCT02996591 Completed - Pain Clinical Trials

Spinal Versus General Anesthesia With Popliteal and Adductor Canal Blocks for Ambulatory Foot and Ankle Surgery.

LMA vs Spinal
Start date: January 2017
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine if there is a difference in patient outcomes with general anesthesia versus spinal anesthesia when given in addition to popliteal and adductor canal nerve blocks for foot and ankle surgery. Popliteal and adductor canal nerve blocks are injections of local anesthetic agents near nerves in the back and front of the knee going to the foot and ankle that provide numbness during and after surgery. These peripheral nerve blocks offer good pain control and reduce the need for opioids (opioids are pain medications such as morphine, Dilaudid, and oxycodone). General anesthesia involves the flow of oxygen and anesthesia gas through a tube which, along with additional intravenous medications, causes unconsciousness and unawareness of sensations during surgery. Spinal anesthesia involves an injection of local anesthetic in the lower back, which causes numbness below the waist. In addition to spinal anesthesia, a sedative is typically given intravenously to cause relaxation and sleepiness throughout surgery. General, spinal, and nerve block anesthesia are all routinely used for surgery at the Hospital for Special Surgery. General or spinal anesthesia is typically used in addition to peripheral nerve blocks during foot and ankle surgery to 1) allow the surgeons to use a thigh tourniquet to reduce bleeding, 2) provide anesthesia earlier, and 3) prevent unwanted movement. However, it is unclear whether general or spinal anesthesia provides better patient outcomes when given with peripheral nerve blocks. Some reports show that on its own, spinal anesthesia has advantages over general anesthesia in terms of side effects such as nausea and pain. However, these advantages may also be gained from combining peripheral nerve blocks with general anesthesia. Spinal anesthesia can be associated with headache and backache, although headache and backache can also happen after operations performed with general anesthesia. A previous study at the Hospital for Special Surgery showed low rates of nausea among patients who received nerve blocks with spinal anesthesia, and no nausea among patients who received a nerve block with general anesthesia. Therefore, the primary aim of this study is to determine if, as a treatment, either general or spinal anesthesia has advantages over the other treatment in terms of readiness for discharge, side effects, pain and patient satisfaction in an ambulatory foot and ankle population.

NCT ID: NCT02995447 Recruiting - General Anesthesia Clinical Trials

Differential Effects of Propofol on Scalp and Intracranial EEG

Start date: November 2012
Phase: N/A
Study type: Observational

The anesthetic propofol has a dose-depending effect on the EEG, which differs in comparison between scalp and intracerebral electrodes

NCT ID: NCT02987985 Completed - Anesthesia Clinical Trials

Efficacy of Opioid-free Anesthesia in Reducing Postoperative Respiratory Depression in Children Undergoing Tonsillectomy

Start date: October 15, 2017
Phase: Phase 3
Study type: Interventional

The objective of this trial is to determine whether an opioid-free general anesthetic (OFA) technique utilizing ketamine, dexmedetomidine, lidocaine, and gabapentin can help reduce postoperative respiratory depression in the post-anesthesia care unit and ward in children with sleep-disordered breathing undergoing tonsillectomy when compared with traditional opioid-containing techniques. It is expected that this OFA regimen will have a measurable reduction on postoperative respiratory depression in children with sleep-disordered breathing.

NCT ID: NCT02822417 Completed - General Anesthesia Clinical Trials

Clinical and Genetic Factors on the Postoperative Recovery Time of General Anaesthesia

Start date: June 1, 2016
Phase:
Study type: Observational

To evaluate the effect of clinical factors on the recovery time of postoperative anesthesia and the effect of genetic variation in gDNA on the recovery time of postoperative anesthesia.

NCT ID: NCT02771067 Completed - General Anesthesia Clinical Trials

The Utility of Pulse Pressure Variation to Predict the Fluid Responsiveness During Pneumoperitoneum and Reverse-Trendelenburg Position

Start date: September 29, 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the validity of pulse pressure variation to predict fluid responsiveness in patients undergoing robotic or laparoscopic gastrectomy.

NCT ID: NCT02762890 Completed - General Anesthesia Clinical Trials

Comparison of Deep Neuromuscular Block and Moderate Neuromuscular Block on Quality of Recovery in Patients Undergoing Robotic Gastrectomy

Start date: October 6, 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate and compare the postoperative quality of recovery between the deep neuromuscular blockade and moderate neuromuscular blockade during robotic gastrectomy.

NCT ID: NCT02754531 Completed - General Anesthesia Clinical Trials

Ultrasonography vs Cole Formula to Predict Endotracheal Tube Diameter

Start date: May 2016
Phase: N/A
Study type: Interventional

This study aims to compare the accuracy of measurement between ultrasonography and Cole formula in predicting uncuffed endotracheal tube diameter.

NCT ID: NCT02745964 Terminated - General Anesthesia Clinical Trials

A Comparison of LMA-Supreme and I-gel for the Incidence of Postoperative Sore Throat

Start date: May 9, 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate and compare the incidence of the postoperative sore throat between LMA supreme and I-gel.