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NCT06269302 Clinical Trial

Comparison of the Effect of Warfarin and Direct Oral Anticoagulants

Gastrointestinal Hemorrhage Clinical Trial

Official title:
Comparison of the Effect of Warfarin and Direct Oral Anticoagulants on Upper Gastrointestinal System Bleeding

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT06269302
Other study ID # 2
Secondary ID
Status Completed
Phase
First received
Last updated
Start date January 1, 2022
Est. completion date December 31, 2022

Study information
Verified date February 2024
Source Samsun Education and Research Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

In this study, it was aimed to compare the frequency of new oral anticoagulants and warfarin usage, and to reveal the rates of recurrent upper gastrointestinal bleeding among patients who applied to our hospital with upper gastrointestinal bleeding

Description:

The data of all patients who applied to Samsun Training and Research Hospital Internal Medicine with a diagnosis of upper gastrointestinal bleeding and hospitalized by Internal Medicine and Gastroenterology clinics or who underwent outpatient endoscopy between 01.01.2021 and 31.12.2021 were included. The patients' data were analyzed from the patient files and hospital automation system retrospectively. Patients who had recurrent upper GI bleeding were detected by controlling them over the hospital software system and by reaching each patient again. The frequency of the new generation oral anticoagulants usage in patients with re-bleeding was determined, and data such as re-bleeding rate, length of hospital stay, need for transfusion, and mortality were analyzed in the groups who did not use this drug and those who used it. The patient demographics were also compared between the groups who were using the new generation oral anticoagulants, acetylsalicylic acid or warfarin.

Recruitment information / eligibility
Status Completed
Enrollment 346
Est. completion date December 31, 2022
Est. primary completion date December 31, 2022
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - Age >18 years old - Upper gastrointestinal bleeding - 12 months follow-up Exclusion Criteria: - Age <18 years old - Lower gastrointestinal bleeding - Esophageal variceal bleeding

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
Turkey Samsun Education and Research Hospital Samsun Ilkadim

Sponsors (1)
Lead Sponsor Collaborator
Samsun Education and Research Hospital

Country where clinical trial is conducted

Turkey, 

Outcome
Type Measure Description Time frame Safety issue
Primary Change in the incidence of recurrent bleeding Increase or decrease in the incidence of recurrent bleeding 12 months
See also
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