Clinical Trials Logo

Gastric Emptying clinical trials

View clinical trials related to Gastric Emptying.

Filter by:

NCT ID: NCT01350284 Completed - Diabetes Mellitus Clinical Trials

The Effect of Natural Food Flavourings on Gastrointestinal and Cardiovascular Physiological Responses.

CinnGastEmpt
Start date: June 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether 3 g cinnamon was sufficient to delay the gastric emptying rate of a high-fat solid meal and subsequently reduce postprandial blood glucose and lipid responses, oxidative stress, arterial stiffness and satiety responses in a healthy adult population.

NCT ID: NCT01139216 Completed - Clinical trials for Functional Constipation

Effect of TU-100 on Rectal Compliance, Rectal Sensation and Small Bowel and Colonic Transit in Females With Constipation

Start date: August 2010
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to assess the dose-related effects of TU-100, a botanical agent that modulates gastrointestinal nerves, on rectal compliance, rectal sensation thresholds and small bowel and colonic transit in female patients with functional constipation as compared to placebo.

NCT ID: NCT01133691 Completed - Gastric Emptying Clinical Trials

Examination of Gastric Emptying in Children

Start date: May 2010
Phase: N/A
Study type: Observational

- Background: Fasting is mandatory for safety of anesthesia in elective surgery and imaging but gives rise to discomfort, hunger and thirst especially in children. Internationally accepted fasting times are often prolonged because of organisational delay in operating theatre. - Hypothesis: Clear fluids can be ingested until an imaginary anesthesia induction time without enlarging the residual gastric contents compared to overnight fast. There is no difference between residual gastric contents after 4 hours of fasting after a light meal compare to 6 hours in healthy children. - Examination of gastric volume using magnetic resonance imaging after overnight fasting and subsequent scans after either clear fluid intake or intake of a standard breakfast are performed in children aged 6 - 12 years. Time course after fluid intake is followed with scans every half hour for 2 hours. In the breakfast group 4 versus 6 hours fasting time will be simulated, e. g. intake of clear fluid is allowed for 2 versus 4 hours after the meal. Volume of gastric contents will be compared with a standardized ultrasonographic view of the stomach.

NCT ID: NCT01117311 Completed - Obesity Clinical Trials

Vagal Nerve Stimulation and Glucose Metabolism

Start date: March 2011
Phase: N/A
Study type: Interventional

The overall aim of this application is to determine the mechanism(s) by which common bariatric surgical procedures alter carbohydrate metabolism. The study proposed will examine the effect of vagal nerve stimulation on insulin secretion and action.

NCT ID: NCT01084473 Completed - Healthy Clinical Trials

Effect of Dexmedetomidine on Gastric Emptying and Gastrointestinal Transit

GADEX
Start date: March 2010
Phase: Phase 1
Study type: Interventional

The aim of the study is to determine the effect of dexmedetomidine infusion on gastric emptying and oro-caecal transit time in healthy volunteers, judged by measuring plasma paracetamol concentrations after paracetamol ingestion and pulmonary hydrogen measurement technique after lactulose ingestion. The effects of dexmedetomidine will be compared to the effects of morphine and placebo.

NCT ID: NCT00980083 Completed - Healthy Subjects Clinical Trials

GLP-1 - Regulatory Mechanism of Postprandial Glycemia

Start date: October 2004
Phase: Phase 1
Study type: Interventional

Synthetic GLP-1 lowers postprandial (pp) glycemia by stimulating insulin, inhibiting glucagon, and delaying gastric emptying. However, the effects of the endogenous peptide are largely unknown. Using the specific GLP-1 receptor antagonist exendin(9-39)amide (Ex(9-39)) the investigators recently showed that GLP-1 released during intestinal meal perfusion acts as an incretin hormone and as an enterogastrone. As the relative contributions of these effects to controll postprandial glycemia are unclear, the investigators used Ex(9-39) to investigate the mechanisms of action of GLP-1 after an oral meal in humans.

NCT ID: NCT00940849 Completed - Gastric Emptying Clinical Trials

Gastric Emptying and Gallbladder Motility Study

Start date: October 2009
Phase: N/A
Study type: Interventional

Background of the study: Plant sterols can play an important role in lowering plasma cholesterol. The extent to which plant sterols can reduce plasma cholesterol levels depends on the intake scenario. We suggest that the difference in these effects depends on gastric emptying and bile secretion. Objective of the study: The aim of this study is to gain insight in the mechanisms that may be involved in the effects of plant sterol drinks on gastric emptying and gallbladder motility. In order to test this, we compare the different effects of the consumption of a plant sterol containing drink prior to, during and after a standardized meal.

NCT ID: NCT00896246 Completed - Healthy Clinical Trials

Scintigraphic Assessment Following Klean-Prep® or Moviprep®

Start date: September 2006
Phase: Phase 1
Study type: Interventional

This was a phase 1, open-label, randomized study, designed to assess the impact of Moviprep® or Klean-Prep® on gastrointestinal transit. It was performed in two parallel groups with Part A in two groups of four subjects preceding Part B, which was performed in two groups of 12 subjects. Subjects attended a pre-study medical within 28 days of dosing and a post-study medical 5-10 days after the final dose. Within both Part A and Part B, subjects were required to attend the clinical unit for 2 study periods. Part A consisted of a baseline period to determine individual reference times for gastrointestinal transit. Part B was the test period in which gastrointestinal transit following the administration of the test preparations was assessed.

NCT ID: NCT00827216 Completed - Gastric Emptying Clinical Trials

The Effect of Intravenous Erythromycin on Gastric Emptying in Non-fasted Patients Before Emergency Total Anesthesia

Start date: January 2009
Phase: Phase 2
Study type: Interventional

In this study the investigators want to investigate the effect of a short intravenous infusion of Erythromycine on gastric emptying on patients considered "full stomac" and scheduled for Emergency operation. A gastroscopy will be done after intubation to controll the effect of the perfusion.

NCT ID: NCT00276406 Completed - Diabetes Mellitus Clinical Trials

Use of Pyridostigmine for Constipation in Diabetics

Start date: May 2006
Phase: Phase 1/Phase 2
Study type: Interventional

Doctors at Mayo Clinic are doing this study to learn if pyridostigmine, a drug, affects the speed at which food travels through the stomach, intestines and colon, and if pyridostigmine improves constipation symptoms in patients with diabetes. Pyridostigmine has been approved by the Food and Drug Administration (FDA) for routine clinical use, however, its use as proposed in this study is considered investigational.