Gastric Cancer Clinical Trial
Official title:
Long Limb Roux-en Y Reconstruction After Gastrectomy As A Potential Cure for Type 2 Diabetes Mellitus in Non-Obese Gastric Cancer Patients - a Pilot Project to Validate a Prospective Randomized Control Trial
We grafted the concept of metabolic surgery (long limb Roux-en Y reconstruction) into gastric cancer surgery. This study aimed to investigate the safety and efficacy of long limb Roux-en Y reconstruction after gastrectomy in non-obese type II diabetes with gastric cancer.
Type II diabetes in the world is increasing rapidly, and it is known that patients with type
II diabetes with morbid obesity that underwent bariatric surgery have resolution of impaired
glucose metabolism.
In Asia, most type II diabetes are not morbidly obese and still, it is controversy whether
metabolic surgery is effective or not in non-morbid obese patients. As life expectancy is
increased, the number of patients with gastric cancer and T2DM is increased as well.
Recently, we studied the outcome of T2DM after gastrectomy and conventional reconstruction
in non-obese gastric cancer patients.(Kim JW et al, World J Gastroenterol 2012;18:49) The
study was a large-series retrospective study including about 400 patients and the result
regarding DM improvement was not satisfactory. Based on our previous results, it is needed
to find more effective way to resolve the type II diabetes in gastrectomized patients with
gastric cancer.
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Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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