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Functional Neuroimaging clinical trials

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NCT ID: NCT05892224 Recruiting - Obesity Clinical Trials

Study on Brain Function of Obesity Classification

Start date: January 1, 2022
Phase:
Study type: Observational

The purpose of this study was to investigate the differences and similarities of brain function in patients with four subtypes of obesity, and the relationship between brain function changes and complications after weight loss and metabolic improvement. 120 patients with obesity and 30 healthy individuals with normal BMI were enrolled.

NCT ID: NCT05313347 Completed - Obesity Clinical Trials

Neural Correlates of Sensory Specific Satiety

Gusto
Start date: February 1, 2022
Phase:
Study type: Observational

Sensory specific satiety, or the phenomenon that the pleasantness of a particular taste declines when certain types food are consumed to satiety, plays an important role in food choice and meal termination.The rewarding effect of sugar will be investigated in a group of 30 healthy participants with a body mass index ranging from 17.5 to 35kg/m2. A gustatory stimulation paradigm designed to induce sensory specific satiety for glucose will be employed. The aim is to assess neuronal stimulus processing in relation to the sensory satiety level and to investigate the relationship with everyday eating behavior.

NCT ID: NCT04723823 Recruiting - Clinical trials for Functional Neuroimaging

Sensorimotor Imaging for Brain-Computer Interfaces

Start date: August 8, 2019
Phase: N/A
Study type: Interventional

The investigators will use fMRI to map movement activity in motor and somatosensory cortex using enriched imagery in people with chronic tetraplegia. The investigators expect that somatotopic organization of movement activity will be preserved in people with upper limb impairments, which can be quantified using the strength, area, and location of sensorimotor activity. Accurate mapping of the motor and somatosensory cortices using covert stimuli will help guide brain-computer interface (BCI) electrode design and placement. Moreover, these advanced mapping procedures will provide new insights into the functional interactions between sensory and motor areas of the brain after injury or disease.

NCT ID: NCT03809598 Completed - Pregnancy Related Clinical Trials

Roo Study on Mom and Baby Well-Being

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

This study employs a randomized controlled trial of an established intervention, Mindfulness Based Cognitive Therapy (MBCT) adapted for pregnancy, to examine effects on various aspects of maternal psychological stress during pregnancy (magnitude and trajectories of stress) and offspring brain systems integral to healthy and maladaptive emotion regulation. This study considers other potential influences on maternal stress and psychiatric symptomatology, and infant behavior and brain development. The study population is pregnant women aged 21-45, and their infants.

NCT ID: NCT02701933 Completed - Clinical trials for Functional Neuroimaging

Effects of Ketamine on Eye Movements, Perception and Brain Function

Start date: April 2014
Phase: N/A
Study type: Interventional

In this study, the investigators examine the effects of low-dose ketamine on different oculomotor, perceptual and cognitive functions. They also examine effects on concurrent brain activity using blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI). A sample of N=25 healthy, male participants is required to complete the study. The design is within-subjects, placebo-controlled, double-blind and cross-over. A targeted ketamine level in plasma of 100ng/ml is applied. It is hypothesised that ketamine, compared to placebo, will lead to changes in task performance and brain activity similar to those observed in patients with schizophrenia.