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Fractures, Closed clinical trials

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NCT ID: NCT05655130 Terminated - Fractures, Bone Clinical Trials

Distal Radius Steroid

Start date: November 6, 2018
Phase: Phase 1
Study type: Interventional

The primary goal of this study is to compare functional outcomes (range of motion [flexion, extension, supination, pronation], return to work, of patients with distal radius fractures who receive intraoperative glucocorticoids to those that do not. Secondary goals include comparison of pain control (number of pain pills consumed, visual analog scale (VAS) pain scores) between patients with distal radius fractures who receive intraoperative glucocorticoids to those that do not. The primary endpoint of this study will occur when 18 patients in each test-group complete the 6 month follow up visit for study.

NCT ID: NCT03781817 Terminated - Trauma Clinical Trials

Intranasal Versus Intravenous Ketamine for Procedural Sedation in Children With Non-operative Fractures

Start date: September 9, 2019
Phase: Phase 4
Study type: Interventional

This a randomized clinical trial involving children with non-operative fractures presenting the emergency department randomized either to intranasal or intravenous ketamine.

NCT ID: NCT03673358 Terminated - Pain, Postoperative Clinical Trials

Cognitive Behavioural Therapy to Optimize Post-Operative Recovery Pilot

COPE Pilot
Start date: January 9, 2019
Phase: N/A
Study type: Interventional

Psychological factors such as stress, distress, anxiety, depression, and poor coping strategies may be associated with ongoing pain following injuries such as fractures. To study this relationship, patients will undergo cognitive behavioural therapy (CBT) which is designed to modify such thoughts with the goal of reducing ongoing pain and improving quality of life. The goal of this study is to determine if CBT, versus usual care, reduces the prevalence of moderate to severe persistent post-surgical pain (PPSP) over 12-months post-fracture

NCT ID: NCT03196258 Terminated - Pain, Postoperative Clinical Trials

Cognitive Behavioural Therapy to Reduce Persistent Post-Surgical Pain After Fracture

SPOC_CBT
Start date: October 1, 2018
Phase: N/A
Study type: Interventional

Psychological factors such as stress, distress, anxiety, depression, and poor coping strategies may be associated with ongoing pain following injuries such as fractures. In order to study this relationship, researchers at McMaster University have developed the Somatic Pre-Occupation and Coping (SPOC) questionnaire, which identifies illness beliefs that may help to predict which patients are at risk for ongoing pain, reduced quality of life, and delays in returning to work and leisure activities after a fracture requiring surgical treatment. Previous research using the SPOC questionnaire suggests the possibility that fracture patients with illness beliefs that put them at risk for developing ongoing pain could be identified early in the treatment process. These patients may benefit from cognitive behavioural therapy (CBT) which is designed to modify such thoughts with the goal of reducing ongoing pain and improving quality of life. The goal of this study is to determine if CBT is effective in reducing ongoing pain and improving quality of life in fracture patients who show illness beliefs that may place them at risk for developing ongoing pain.

NCT ID: NCT02597972 Terminated - Clinical trials for Closed Fracture Proximal Humerus, Four Part

Reverse Total Shoulder Arthroplasty Versus Open Reduction Internal Fixation of 3&4 Part Proximal Humerus Fractures

Start date: September 2015
Phase: N/A
Study type: Interventional

Will patients who suffer complex humerus fractures have better functional outcomes and less implant failure with shoulder replacement (reverse total shoulder arthroplasty, RTSA) compared to shoulder repair (open reduction and internal fixation, ORIF)?

NCT ID: NCT02027532 Terminated - Infection Clinical Trials

Prevention of Infection in Closed Fractures: Cefazolin Versus Vancomycin

Start date: October 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the incidence rate of infection in surgical patients with closed fractures treated prophylactically with Cefazolin versus Vancomycin in the peri-operative period. The hypothesis of this study is that patients undergoing surgical treatment for closed fractures who are treated prophylactically with Vancomycin will have a lower incidence rate of infection than patients who are treated prophylactically with Cefazolin.

NCT ID: NCT00610701 Terminated - Fractures, Closed Clinical Trials

Lateral Versus Anterior Spanning External Fixator for Tibial Plateau Fractures

Start date: March 2006
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate patients with tibial plateau fractures.