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Fractures, Bone clinical trials

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NCT ID: NCT01473082 Completed - Hip Fractures Clinical Trials

Proximal Femoral Nail Antirotation (PFNA) Versus PFNA Augmentation

Start date: February 2012
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate whether patients with trochanteric fractures being treated with a Proximal Femoral Nail Antirotation (PFNA) and augmentation can better be mobilized than patients without augmentation.

NCT ID: NCT01444144 Completed - Ankle Fracture Clinical Trials

Ankle Fracture Treatment in the Elderly

Start date: March 2011
Phase: N/A
Study type: Observational

The purpose of this study is to track surgical outcomes and post-operative course in patients 55 years of age or older treated for ankle fractures.

NCT ID: NCT01441817 Completed - Fracture of Ankle Clinical Trials

Non--operative Treatment of the Medial Malleolus in bi- and Trimalleolar Ankle Fractures

Start date: May 2002
Phase: N/A
Study type: Interventional

The purpose of this study was to determine if internal fixation of the medial malleolus is necessary following open reduction and internal fixation of the lateral and, if required, the posterior malleolus treating displaced bi-or trimalleolar ankle fractures.

NCT ID: NCT01437150 Completed - Clinical trials for Fracture of Acetabulum

Treatment of Acetabular Posterior Wall Fracture With Anatomical Locking Plate

Start date: August 2011
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether this new anatomical locking plate is more effective and easy to operate than other plate in the treatment of acetabular posterior wall fracture.

NCT ID: NCT01431560 Completed - Ankle Fracture Clinical Trials

Outcomes of Operative Treatment of Unstable Ankle Fracture - Comparison Between Metallic and Biodegradable Implants

Start date: June 2008
Phase: Phase 4
Study type: Interventional

The purposes of this study are to compare the outcomes of the biodegradable implants for the fixation of ankle fracture and those of metallic implants, and to assess the problems of the biodegradable implants. Null hypothesis is that the clinical outcomes of biodegradable plate and screws for ankle fracture are not different from those of metallic implants.

NCT ID: NCT01410032 Completed - Clavicle Fracture Clinical Trials

Reconstruction Plate Compared With Flexible Intramedullary Nailing for Midshaft Clavicular Fractures

Start date: July 2010
Phase: Phase 2
Study type: Interventional

The purpose of this study is to compare the clinical and radiographic results of patients with midshaft clavicular fractures treated with plates or intramedullary flexible nails fixation.

NCT ID: NCT01408693 Completed - Clinical trials for Femoral Neck Fracture

Minimal Invasive Anterior Approach Versus Trans-gluteal Approach for Hemi-arthroplasty in Femoral Neck Fractures

MIS-CLAS
Start date: August 2011
Phase: Phase 4
Study type: Interventional

The aim of the study is to test the hypothesis that patients older than 60 years with a femoral neck fracture eligible for hemi-arthroplasty (HA) operated by an anterior minimal-invasive approach as compared to a standard lateral Hardinge approach show better functional recovery postoperatively as measured by the "Timed up and go"-test (TUG).

NCT ID: NCT01405703 Completed - Clavicle Fracture Clinical Trials

Percutaneous Versus Open Plate Fixation of Diaphyseal Clavicle Fractures

Start date: July 2011
Phase: N/A
Study type: Observational

This is a prospective, level II evidence comparison between two cohorts. This study is designed to compare the percutaneous versus open approach for plate fixation of diaphyseal clavicle fractures. This study includes questionnaires and measurements that will collect data on incision-related numbness, union rates, overall outcomes, complication rates of the two methods, infection rates, and overall satisfaction. The surgical procedure, all radiographs and follow-up visits to a minimum of one year are the principle investigators (PI's) standard of care for this injury. Measurements and questionnaires are related to the study.

NCT ID: NCT01404195 Completed - Sarcopenia Clinical Trials

Hyperprotein Nutritional Intervention in Elderly Patients With Hip Fracture and Sarcopenia

HIPERPROT
Start date: January 2012
Phase: N/A
Study type: Interventional

1. RATIONALE The unique characteristic of our study lies in the attempt to reverse the functional impairment experienced by sarcopenic patients with hip fracture using nutritional intervention. What makes this study different from prior studies is that it will be conducted in a hospital setting, unlike most prior studies, which were conducted in a community setting. The association between muscle mass and strength, inflammatory indices, and functional impairment versus dependence and fragility will also be measured. 2. HYPOTHESIS The hypothesis of our study is that nutritional intervention enriched in metabolites of essential amino acids (beta-hydroxy-beta-methylbutyrate) is effective for treating sarcopenia in elderly patients with hip fracture and improves functional level. 3. OBJECTIVES Primary objective is to assess functional improvement after nutritional intervention in sarcopenic patients with hip fracture, as measured using Barthel index. Secondary objectives will include: 1) to show the relationship between metabolic and inflammatory indices and sarcopenia; 2) to show how sarcopenia and its treatment influence the risk of fall; 3) to show muscle mass improvement; 4) to show increased strength; 5) to assess mortality and morbidity. 4. EXPECTED RESULTS The investigators expect to find that the supplemented group experiences throughout the study period a significant improvement in functional status (Barthel index), an increase in muscle mass, and a reduction in fat mass. An increased strength and a reduction in associated complications (falls) are also expected. The investigators hope to be able to show reductions in inflammatory indices and insulin resistance. To conclude, by improving muscle strength and mass the investigators expect to find a reduction in the disability and dependence of this population group.

NCT ID: NCT01394809 Completed - Clinical trials for Osteoporotic Distal Radius Fracture

Effects of Motor Cognitive Training on Functional Loss After Osteoporotic Wrist Fractures

PROFinD-TP4
Start date: August 2010
Phase: N/A
Study type: Interventional

The therapy results after distal radius fracture especially of elderly patients are often suboptimal. The central problem results from the inevitable, 3-6-weeks immobilization, which leads to reduction in ROM of the wrist, deterioration of muscle strength as well as malfunction of fine motor skills and coordination. Currently, there are no adequate proactive strategies to counteract these immobilisation problems. Hence the overall aim of our research project is to investigate the therapeutic potential of a motor-cognitive therapy on hand function after distal radius fracture. On the one hand the pilot study should provide information about the level of recruitment rate necessitated for an adequate sample size which allows reliable evidence for the therapy effects. On the other hand we want to evaluate the sensitivity and adequacy of the assessment instruments. The pilot is conceived as a controlled, randomised, longitudinal intervention study over 6 weeks with 3 groups. One experimental group imagine movements and actions without executing them. A second experimental group performs mirror training, in which visual feedback through a mirror activates additionally the contralateral hemisphere. The control group receives therapy as usual. There are three key domains to be analysed: function (PRWE), impairment (ROM, strength) and participation in social life/life quality (DASH, EQ5D).