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Fractures, Bone clinical trials

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NCT ID: NCT01690780 Completed - Clinical trials for Upper Extremity Fractures

Oral Morphine Versus Ibuprofen

Start date: September 2012
Phase: N/A
Study type: Interventional

Children 5-17 years of age who have sustained a non-operative distal forearm (radius and/or ulna) or clavicular fracture will be randomized to receive either ibuprofen or oral morphine as needed for pain relief for the first 24 hours following discharge from the emergency department. Pain will be assessed using the self-report Faces pain scale revised (FPS-R). We hypothesize that oral morphine will result in greater pain relief than ibuprofen.

NCT ID: NCT01673776 Completed - Clinical trials for Proximal Femoral Fracture

Multimodal Approach to Improve the Outcome of Patients With a Proximal Femoral Fracture

FEMO
Start date: March 2012
Phase: N/A
Study type: Interventional

This study is designed to compare the outcome of patients with proximal femoral fractures with different perioperative regimes: a group with a multimodal intervention and a control group.

NCT ID: NCT01673048 Completed - Children Clinical Trials

Modification of ESIN-osteosynthesis in a Femoral Fracture Model and Its Transmission to Clinical Practice

ESIN
Start date: January 2009
Phase: N/A
Study type: Interventional

Elastic stable intramedullary nailing (ESIN) is the standard treatment for displaced diaphyseal femoral fractures in children. However, some literature report high complication rates (10-50%) in complex fractures. Data of our own patients with special emphasis on complications showed also mediocre results. Thus, a biomechanical study was conducted to search for modifications. In this study the stiffness with a 3rd nail implanted was compared to the classical 2 C-shaped configuration. For each of the 3 configurations of retrograde ESIN (titanium nails) eight composite femoral grafts (Sawbones®) with an identical spiral fracture were used: 2C configuration (2 C-shaped nails, 2x3.5 mm), 3CM configuration (3rd from antero-medial, + 1x2.5 mm) and 3CL configuration (3rd from antero-lateral, + 1x2.5 mm). Each group underwent biomechanical testing in 4-point bending, IRO/ERO and axial compression (0°/9°). Due to a significantly higher stiffness of 3CL in the anterior-posterior, internal rotation and 9° compression directions implantation of 3 nails became standard treatment for all dislocated femoral fractures at our department. All patients were followed prospectively. The following data was collected: Type of osteosynthesis, any kind of complication (additional procedures like cast or external fixateur, Re-Do operations, misalignment, pseudarthrosis, skin irritation, infection), time until full weight bearing and time until implant removal. At follow-up the legs were controlled for a possible length discrepancy and a possible deviation of axis. Patients` satisfaction was controlled by CSQ (clients satisfaction score, Larsen et al 2002). Further on the Harris Hip Score was used. X-ray controls were done as standard care protocol after 1 and 3-4 months (dependend on age). Level of Evidence IV Keywords: Elastic stable intramedullary nailing, biomechanical testing, fracture, femur, treatment, children, adolescents.

NCT ID: NCT01667887 Completed - Clinical trials for Fracture of Distal Femur

Plating of Distal Femur Fractures by Far Cortical Locking Using MotionLoc Screws

Start date: April 2011
Phase: N/A
Study type: Observational

The objective of this study is to document callus formation and healing of fractures stabilized with locking plates utilizing modern MotionLoc screws that provide controlled axial micro-motion to actively promote fracture healing.

NCT ID: NCT01650064 Completed - Hip Fractures Clinical Trials

Latin America Hip Fracture Mortality Study

LAMOS
Start date: January 2013
Phase:
Study type: Observational

The purpose of this study is to estimate the survival proportion one year after surgery for intertrochanteric fracture in older adults in Latin America.

NCT ID: NCT01643395 Completed - Clinical trials for Vertebral Compression Fracture

VertebrOpLasty Versus Conservative Treatment in Acute Non Osteoporotic Vertebral Fractures

VOLCANO
Start date: September 2010
Phase: Phase 3
Study type: Interventional

The purpose of this protocol is to prove the efficacy of vertebroplasty in patients suffering from acute non osteoporotic vertebral compression fracture. Vertebroplasty consists in the injection of cement (PMMA) in the damaged vertebral body to prevent further collapse. Our study will compare vertebroplasty versus conservative therapy (brace).

NCT ID: NCT01630343 Completed - Clinical trials for Geriatric Hip Fracture Pain Management

Pain Management in Geriatric Hip Fracture

Start date: January 2010
Phase: Phase 2
Study type: Interventional

The Null Hypothesis is that there is no association between Pain regime and the functional performance among geriatric patients having traumatic hip fracture. Two limbs are being assessed:1. Three weeks of regular oral Panadol and Tramadol after hip fracture 2. Oral Panadol and tramadol taking in p.r.n. basis. Functional outcome including Numerical Rate Scale for pain assessment, Functional Independency Measure and Elderly Mobility Score are chosen.

NCT ID: NCT01627483 Completed - Hip Fracture Clinical Trials

Randomized Controlled Trial of Effects of Physician's Medication Reviews on Prescribing in Older Hip Fracture Patients

Start date: April 2009
Phase: N/A
Study type: Interventional

The aim of this study is to investigate if prescribing of fall-risk increasing and fracture-preventing drugs can be improved in older hip fracture patients by assessments of risks of falls and fractures and medication reviews performed by a physician and forwarded to prescribing physicians.

NCT ID: NCT01618786 Completed - Clinical trials for Traumatic Brain Injury

Flooring for Injury Prevention Trial

FLIP
Start date: September 1, 2013
Phase: N/A
Study type: Interventional

This study will evaluate the efficacy of novel compliant flooring in reducing injuries due to falls in a long-term care facility, determine the cost effectiveness of this intervention, and assess perceptions about compliant flooring among staff, residents, and families. The investigators hypothesize that compliant flooring will (1) reduce the incidence of injuries due to falls in long-term care residents; (2) represent an overall cost-savings when material and implementation costs are considered relative to direct and indirect costs associated with injuries due to falls; and (3) be received positively by staff, residents, and their family members.

NCT ID: NCT01616030 Completed - Hip Fractures Clinical Trials

Early Strength Training After Hip Fracture Surgery

Start date: June 2012
Phase: N/A
Study type: Interventional

Patients treated surgically for a hip fracture have a need of rehabilitation for the regain of former functional skills. Despite an optimized fast track in-hospital rehabilitation program it has been found that patients with hip fracture within 2 weeks after the hip fracture loose more than half of their muscle strength in the fractured limb compared to non-fractured limb. New studies including patients with total hip arthroplasty and strength training applied early after surgery has shown promising results regarding prevention of loss of muscle strength. No similar study has been found including patients with hip fracture. The purpose of this study is to examine the feasibility of progressive knee-extension strength training of the hip fractured limb, starting Day 1 after surgical treatment for a hip fracture and proceeded every weekday during their hospital stay. The study will include 20 patients surgically treated for a cervical hip fracture and 20 patients surgically treated for an intertrochanteric or subtrochanteric fracture. All patients are admitted from their own home. Age 60 years or older.