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Fractures, Bone clinical trials

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NCT ID: NCT05817916 Completed - Femur Fracture Clinical Trials

Comparison of Erector Spina Plane Block and Lumbar Plexus Block in Femoral Fracture Surgery

Start date: April 15, 2023
Phase: N/A
Study type: Interventional

The aim is to clinical trials compare the lumbar plexus block method with the erector spinae plan block method in terms of analgesic efficacy and possible complications. İn patients for femur fracture surgery. The main questions it aims to answer are: 1. is erector spinae plane block as effective as lumbar plexus block for postoperative analgesia in femur fractures? 2. Is erector spinae plane block effective for reducing opioid consumption compared to lumbar plexus block?

NCT ID: NCT05810012 Completed - Clinical trials for Hip Fracture Surgery

Comparison of Analgesic Efficacy of PENB Block With FICB in Post Operative Hip Fracture Patients

Start date: April 1, 2022
Phase: Phase 2
Study type: Interventional

This study was done to evaluate two different interventions for postoperative pain control in patients undergoing hip surgeries. Fifty patients, divided in two equal groups, were included in the study. Patients in Group P were given pericapsular nerve group (PENG) block while those in Group F were given fascia iliaca compartment block (FICB). Pain score, using Numeric Rating scale as a measurement tool, was assessed at one, six, eighteen and twenty fours after the procedure as a primary outcome. Total tramadol consumption in milligrams was recorded as a secondary outcome.

NCT ID: NCT05804604 Completed - Bone Loss Clinical Trials

Bone Intake Proteins and Muscle Mass Deficiency in Proximal Femur Fractures

Start date: May 7, 2022
Phase:
Study type: Observational

The aim of this clinical trial is to compare serum concentration of bone intake proteins [ sex hormone-binding globulin (SHBG), cross linked C-telopeptide of type I collagen (CTX-I)] and muscle atrophy marker [creatine kinase (CK-MB)] between patients after the fracture of proximal femur and their age corresponding counterpart without the fracture. The main question it aims to answer is: • Is the higher concentration of bone intake proteins and muscle atrophy marker a predictive factor of proximal femur fracture? The part of participants (Group 1) will be hospitalized at the Department of Orthopaedics and Rehabilitation and will undergo a surgical treatment (open reduction of the fracture). The rest (Group 2) will be admitted to the Department of Internal Medicine. Participants of both Groups will have the blood sample test taken, to evaluate and compare the serum concentration of SHBG, CTX-I and CK-MB proteins.

NCT ID: NCT05803681 Completed - Vertebral Fracture Clinical Trials

CCEF in the Treatment of Acute VFFs: Randomized Controlled Trial

Start date: January 1, 2015
Phase: N/A
Study type: Interventional

in recent years the search for therapeutic protocols that could enhance the VFFs healing, thus reducing bed rest-related complications and improving the quality of life of osteoporotic patients. In this context, biophysical stimulation with Capacitively Coupling Electric Fields (CCEF) together, antiresorptive therapy, vitamin D supplementation, and analgesic drugs could play a central role. CCEF is a non-invasive type of biophysical stimulation used to enhance fracture repair and spinal fusion. Positive effects of CCEF have been reported in osteoporotic vertebral fractures to resolve chronic pain and in postoperative pain, disability, and quality of life after spinal fusion In a preliminary observational study, Piazzolla et al. showed a significantly faster VBME resolution and back pain improvement in patients suffering from VFFs.

NCT ID: NCT05786079 Completed - Clinical trials for Tibial Stress Fracture

Effects of Footstrike Transition on Tibial Stress Fracture Risk

Start date: June 1, 2016
Phase: N/A
Study type: Interventional

Biomechanical literature suggests that runners who utilize a mid or forefoot strike pattern may suffer from a reduced incidence of chronic injuries compared to a rearfoot strike. This investigation examined the effects of a 10-week footstrike transition intervention on tibial stress fracture risk in runners.

NCT ID: NCT05770856 Completed - Infections Clinical Trials

Clinical Metagenomic of Post-traumatic Infections

METADIAG
Start date: April 27, 2023
Phase:
Study type: Observational

Treatment of fracture related infection is challenging and often lead to failure in such situation that carry a high health cost burden. These infections are often polymicrobial, making the identification of all involved microorganisms a major concern to provide tailored antibiotic treatment. Culture-independent methods are needed to better represent the microbial diversity of infected wounds. Metagenomic sequencing might lead to an accurate microbiome characterization in infected trauma-related wound. Preliminary studies have reported results of metagenomic sequencing in diabetic foot infection but data focusing on non-diabetic infected patients are scarce. The impact of post-traumatic infected wound microbiome needs to be assessed, with regards to bacterial abundance, diversity including at the strain level and functional genes, along with their longitudinal evolution and association with clinical outcomes.

NCT ID: NCT05756517 Completed - Hip Fractures Clinical Trials

Basic Mobility and Physical Activity During Hospitalization for a Hip Fracture: Functions Needed and Strategies Used

HIP-ME-UP
Start date: March 8, 2023
Phase:
Study type: Observational

Present study aim to gain an understanding of functions needed and strategies used for patients following hip fracture surgery to be independent in basic mobility activities during acute hospitalization, and establish knowledge of how much (or little) patients get out of bed. Within the patients included in this cohort study (1), a subgroup will also be included in a satellite study (2), with a separate objective. Definitions are presented in the detailed description below (objectives 1-2).

NCT ID: NCT05754320 Completed - Olecranon Fracture Clinical Trials

TBW vs Plating in Olecranon Fractures

Start date: November 10, 2012
Phase: N/A
Study type: Interventional

Background: While the tension band wiring (TBW) technique is commonly used for simple, displaced olecranon fractures, it is associated with complications such as hardware prominence. To date, studies comparing between the efficacy and safety of TBW and plate fixation for these fractures have not provided a conclusive answer. Purposes: To investigate which of the two techniques provide better functional and radiological outcomes for simple displaced Mayo type 2A olecranon fractures, Which technique provides better patient-reported outcomes, What are the complication rates associated with each technique

NCT ID: NCT05737459 Completed - Clinical trials for Cognitive Impairment

Sedation and Postoperative Cognitive Functions

Start date: May 1, 2022
Phase:
Study type: Observational [Patient Registry]

Patients over the age of 65 who underwent elective surgery for a hip fracture and were sedated during spinal anesthesia were included in the study. Patients who were given ketamine and dexmedetomidine for sedation were included in the study. The Mini Mental Status Tests of the patients measured on the first and third days of the operation in the preoperative period were determined from the hospital records and recorded.

NCT ID: NCT05735561 Completed - Avascular Necrosis Clinical Trials

Proximal Humerus Fracture Dislocation Direction and Avascular Necrosis

PHF-D
Start date: February 15, 2023
Phase:
Study type: Observational

The purpose of the study is to see if there is a connection between a proximal humerus fracture dislocation direction and the likelihood of developing avascular necrosis. Utilizing a retrospective cohort from the last ten years we hope to bring consenting patients back for a single visit to have x-rays and complete patient reported outcome measures to assess for evidence of avascular necrosis.