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Fractures, Bone clinical trials

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NCT ID: NCT05280639 Recruiting - Ankle Fractures Clinical Trials

Simplified Post Op Rehabilitation for Ankle and Pilon Fractures

Start date: October 3, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to compare standard post operative rehabilitation with a simplified wooden block stretching protocol that will yield similar results.

NCT ID: NCT05279261 Recruiting - Fracture; Glenoid Clinical Trials

Clinical Effect of the Axillary Approach to Glenoid Fractures

Start date: June 12, 2019
Phase: N/A
Study type: Interventional

Glenoid fractures result in glenohumeral post-trauma arthritis and instability. Operative treatment is indicated for severe fractures. The traditional deltopectoral approach, which requires detachment of the subscapularis, has many drawbacks, including loss of external rotation and suboptimal fixation. Arthroscopic techniques also cannot allow anatomic reduction and biomechanical stability for large fractures. We describe an alternative approach that enters from the axilla through the interval between the rotator cuff and the inferior glenoid, neck and lateral border of the scapula without detachment of the rotator cuff.

NCT ID: NCT05274113 Enrolling by invitation - Post Operative Pain Clinical Trials

Low Dose Dexamethasone for Distal Radius Fractures

Start date: March 10, 2022
Phase: Phase 3
Study type: Interventional

The addition of the steroid dexamethasone to a single injection of local anesthetic has been shown to significantly prolong the duration of peripheral nerve blockade compared to local anesthetic alone. This allows for improved post-operative pain scores and reduces opioid use in the early post-operative period. However, the use of a steroid adjuvant in regional nerve blocks is generally not considered standard of care, and there is considerable variation among anesthesiologists regarding preferred formulations and the role of adjuvants in regional anesthesia. A recent study from our institution demonstrated the effectiveness of dexamethasone directly mixed with local anesthetic at multiple doses compared to placebo for upper extremity surgery. With this prospective randomized controlled blinded trial, we hope to definitively establish which method of adjuvant dexamethasone administration is superior in extending the effects of a brachial plexus nerve block.

NCT ID: NCT05274022 Recruiting - Tibial Fractures Clinical Trials

Rehabilitation Strategies to Improve Outcomes For Patients With a Lower Extremity Fracture

RIFLE
Start date: March 3, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate speed high intensity interval training (HIIT) walking program following an orthopedic trauma.

NCT ID: NCT05272631 Recruiting - Tibial Fractures Clinical Trials

Depuy Synthes Lower Extremity Shaft Nail Registry

Start date: May 4, 2022
Phase:
Study type: Observational [Patient Registry]

The purpose of this post-market registry is to monitor the clinical safety and performance (union rates and time to union) of two DePuy Synthes lower extremity shaft nails: RFN-Advanced Retrograde Femoral Nailing System (RFNA) and TN-Advanced Tibial Nailing System (TNA) in participants who have experienced femoral or tibial fractures, respectively, requiring fixation and stabilization or who require a revision due to a malunion or a nonunion.

NCT ID: NCT05272072 Completed - Hip Fractures Clinical Trials

Evaluation of Relationship Between Preoperative Fibrinogen/Albumin Ratio and Morbidity After Hip Fracture Operations

Start date: March 30, 2022
Phase:
Study type: Observational [Patient Registry]

Due to the aging of populations, hip fracture operations are increasing from year to year. This operations have many complications also high morbidity and the mortality. Population of this study is oldest old age patients who will have an operation because of hip fracture. The primary outcome of this study is evaluation of relationship between preoperative fibrinogen/albumin ratio and the morbidity after hip fracture operations. The secondary outcomes of this study is evaluation of relationships between fibrinogen/albumin ratio and mortality, length of stay in ICU, length of stay in hospital, postoperative complications, blood product consumption. The study will be completed after the records of preoperative, intraoperative data and the data of the first 30 days postoperatively in this population.

NCT ID: NCT05269979 Active, not recruiting - Fragility Fracture Clinical Trials

Hip Fracture Prevention Follow-up of Elderly Women in Primary Health Care

HIP22
Start date: November 2001
Phase: N/A
Study type: Interventional

Researchers plan a 2022 follow-up of medical records data to investigate fracture incidence and survival for 1248 women, born 1902-1931, in a comparative fracture prevention study with 435 participants from an intervention area and 813 participants from two control areas. In 2022 researchers want to assess patient records data in intervention and control areas and compare A) Survival B) Risk factors for osteoporotic fractures (wrist, upper arm, vertebral, pelvic, hip) C) physical activity, exercise and drugs that affect fracture risk.

NCT ID: NCT05267977 Suspended - Clinical trials for Lower Extremity Fracture

Antibiotic Use & Open Fracture of the Lower Extremity

Start date: August 2016
Phase: Phase 1/Phase 2
Study type: Interventional

It is important to recognize the potential for renal injury and be cognizant of this during the management of complex trauma patients. The primary aim of this study is to investigate the necessity of aminoglycoside usage for patients with open lower extremity fractures. Hypothesis: adding aminoglycoside on top of cephalosporin in treating lower extremity fracture will make no significant difference in term of clinical outcomes when compared to cephalosporin alone.

NCT ID: NCT05266755 Not yet recruiting - Hip Fractures Clinical Trials

Hospital Readmission After HIPr Fracture. Impact of a Territorial Fracture Liason Service

FLSSantPau
Start date: March 15, 2022
Phase: N/A
Study type: Interventional

The International Osteoporosis Foundation (IOF) and the American Society for Bone Research and Mineral Metabolism recommend the creation and implementation of fracture coordination services (FLS) as the most efficient way to address the problem. FLS has emerged as a new clinical approach that uses coordinated, multidisciplinary care to improve post-fracture outcomes and reduce recurrent fractures. It is a multidisciplinary and protocolized care model that must guarantee: 1. Identify fragility fractures and people at risk for a fracture 2. Fracture risk assessment 3. Indication for treatment or referral 4. Improvement in therapeutic compliance 5. Reduce the risk of falls It is known that patients who have undergone a FLS model (vs no FLS), have lower mortality, lower risk of fracture, with a reduction of 35% and 56%, respectively, during two years of follow-up. One of the most important objectives of the FLS is the proper recognition and treatment of osteoporosis (OP) in patients with fragility fractures. A major problem is the lack of adherence to treatment for OP, and inclusion in an FLS program increases the prescription of bisphosphonates from 17.9% to 76%. In addition, a specific follow-up program means that 73% of patients followed by FLS continue to undergo anti-resorptive treatment after 2 years of having suffered a femur fracture.

NCT ID: NCT05264675 Recruiting - Clinical trials for Distal Radius Fracture

Functional Outcome After EPL-rupture After Distal Radius Fracture

Start date: January 1, 2022
Phase:
Study type: Observational

Rupture of the extensor pollicis longus, (EPL) is a common complication after distal radius fractures. A rupture prevents the thumb extension, which in turn has a negative impact on hand function. An EPL-rupture can either be surgically treated by primary suture, which means that the ends of the tendon are sutured. This is however not recommended if the tendon is weakened. In such cases the rupture can be treated by a transfer of, most often, extensor indicis proprius (EIP) to the thumb. Distal radius fractures are common and a rupture of the EPL-tendon is a known complication thar interferes with hand function and therefore more studies on this patient group are warranted. The aim of this prospective study is to compare regaining of thumb function after surgery, with the non-injured side, after primary suture and EIP-transfer after EPL-rupture as a complication following distal radius fracture.