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Fractures, Bone clinical trials

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NCT ID: NCT06392048 Not yet recruiting - Hip Fractures Clinical Trials

Anesthesia Method on Mortality in Hip Fracture Surgeries in the Elderly: Predictions by Artificial Intelligence

Start date: May 25, 2024
Phase:
Study type: Observational

With increasing life expectancy, the elderly population is growing. Hip fractures significantly increase morbidity and mortality, particularly within the first year, among elderly patients. Managing anesthesia in these elderly patients, who often have multiple comorbidities, is challenging. Identifying perioperative factors that can reduce mortality will benefit the perioperative management of these patients. The investigators aimed to predict the impact of anesthesia management on mortality in hip fracture patients using predictions supported by artificial intelligence.

NCT ID: NCT06388915 Completed - Pelvic Fracture Clinical Trials

A Retrospective Cohort Study of 15 Cases of Pelvic Fractures Complicated by Morel-Lavallee Lesion

Start date: March 12, 2024
Phase:
Study type: Observational

Some related factors of pelvic fracture and Morel-Lavallee injury (MLL) are preliminarily discussed, which provides some preliminary references for early clinical detection and research of such injuries.

NCT ID: NCT06384456 Not yet recruiting - Clinical trials for Distal Radius Fractures

Topical TRanexamic Acid vs. Placebo on Acute Postoperative Pain Following DRF Fixation

TRADR
Start date: August 2024
Phase: Phase 4
Study type: Interventional

The goal of this study is to find out whether the use of topical tranexamic acid (TXA) into the surgical wound will result in less post-operative pain, less pain killer use, and better post-operative use of the wrist in people undergoing surgery for a wrist fracture compared to not using topical TXA (placebo).

NCT ID: NCT06382584 Completed - Surgery Clinical Trials

Impact of Treatment With Oral Anticoagulants of Patients With Fractures of the Upper End of the Femur

ANTI_XA
Start date: January 1, 2022
Phase:
Study type: Observational

In 2023, oral anticoagulant treatments (anti Xa: apixaban , rivaroxaban, etc.) are tending to replace anti vitamin K treatments in many medical indications. Their prescription is increasing rapidly in the elderly. In this context, the Nimes University Hospital receives a large number of elderly patients who have suffered a fracture of the end of the femur requiring surgery and who are taking anti Xa drugs.To avoid massive intra- and post-operative haemorrhage, surgical management is postponed because of the need to suspend the treatment, allowing a return to near-normal biological haemostasis within a few days. No consensus has been reached on the withdrawal period required to authorise surgery, as the elimination kinetics of the drug are altered in this context (elderly patients, dehydration, hypovolaemia, impaired renal function). A plasma assay (threshold of <30 to 60 ng/mL) has been proposed without any real justification. This waiting period exposes the elderly to excess mortality. Reversing these treatments by adding coagulation factors would be an attractive alternative, as it would allow surgery to be performed earlier, but this would expose patients to an increased thrombotic risk. Before considering a prospective randomised study (early vs delayed surgery on AOD), we wish to retrospectively analyse data on patients admitted to the Nimes University Hospital on anti Xa and operated on for fracture of the upper end of the femur between 1 January 2022 and 1 June 2023

NCT ID: NCT06379555 Not yet recruiting - Wrist Fractures Clinical Trials

Wrist Fractures Management With Arthroscopic Assistance Under Walant - Exploratory Study

WALANPOIGNE
Start date: June 2024
Phase: N/A
Study type: Interventional

Wrist articular fractures are more difficult to treat and rehabilitation takes longer. Furthermore, these joint fractures are frequently accompanied by ligament lesions of the carpal bones. For these reasons, it is strongly recommended to check the interior of the wrist joint. This check can be done with wrist arthroscopy. Therefore, fracture reduction can be improved, "step of stairs" can be eliminated under arthroscopic control and ligament rupture of carpal bones can be treated. WALANT anesthesia (Wide Awake Local Anesthesia No Tourniquet) designates a new local anesthesia technique. This technique which allows to maintain the arm or fingers mobility offers several significant advantages: - Greater precision of the surgical procedure. - A reduction in discomfort, risks and related adverse effects to anesthesia. - Faster recovery. WALANT technique is very comfortable for patient and fits perfectly with principles of Enhanced Recovery in Surgery. In this context, this study is based on the hypothesis that it is possible to combine arthroscopy and the WALANT anesthesia technique for reducing wrist fractures

NCT ID: NCT06379490 Recruiting - Lidocaine Clinical Trials

Ultrasound-guided Infraclavicular Block With Lidocaine or Ropivacaine for Closed Reduction of Distal Radius Fractures

Start date: April 23, 2024
Phase: Phase 3
Study type: Interventional

To investigate the feasibility of the lateral infraclavicular plexus brachialis (LIC) block for acute closed reduction of distal radius fractures, the investigators will compare the pain-relieving and muscle-relaxing properties of the LIC block with short- and long-acting local anesthetics in different concentrations but at the same volume. In addition to motor and sensory blockade during repositioning, feasibility will also be assessed by other patient-related and block-related factors, as well as by factors related to the repositioning and plastering procedure.

NCT ID: NCT06379243 Recruiting - Clinical trials for Osteoporosis Fracture

Development and Validation of a Postoperative Re-fracture Risk Model for Osteoporotic Spinal Fractures

Start date: December 1, 2023
Phase: N/A
Study type: Interventional

In this project, IDEAL-IQ technology and PDFF and R2* image-based imaging methods are used to analyze the intrinsic relationship between preoperative vertebral bone marrow fat content, magnetic susceptibility properties of bone tissue and bone strength (bone volume and bone mass), to explore the mechanism of vertebral re-fracture after PVP / PKP, and to explore the imaging markers for the risk of postoperative vertebral re-fracture after PVP / PKP. To construct a precise and individualized risk assessment model of vertebral re-fracture after PVP/ PKP by combining clinical risk factors, preoperative quantitative MRI parameters (PDFF, R2*) and imaging characteristics, so as to achieve the goal of objectively and accurately evaluating the risk of vertebral re-fracture at the early stage of the postoperative period (1 year).

NCT ID: NCT06376682 Not yet recruiting - Bone Metastases Clinical Trials

EPIBONE Study: a Prospective Study on Feasibility, Safety and Accuracy

EPIBONE
Start date: July 1, 2024
Phase: N/A
Study type: Interventional

Interventional clinical study to obtain performance and safety data of the EPIONE® device when used for bone percutaneous procedures.

NCT ID: NCT06374472 Completed - Spine Fracture Clinical Trials

Surgical Treatment of Fractures of the Dorso-lombar Spine

Start date: January 1, 2018
Phase:
Study type: Observational

Trauma to the thoracolumbar spine is responsible for potentially serious lesions, most often involving the functional prognosis in the short, medium and long term, and rare The frequency of these traumas is explained by falls from high places, especially during work accidents or suicide attempts, but also by the perpetual increase in accidents on public roads ly the vital prognosis

NCT ID: NCT06372067 Not yet recruiting - Clinical trials for Hand; Fracture, Phalanx

IM Screw vs. K-wire Fixation of Proximal/Middle Phalanx Fractures

HANDFIX
Start date: July 1, 2024
Phase: N/A
Study type: Interventional

When people break their fingers, sometimes surgery is needed to align the bones to heal them properly. There are different ways to fix broken bones in hands, such as plates, pins, or screws. Each method has pros and cons; fixing a broken bone with plates is usually a larger surgery with more cutting but holds the bones very securely. Pins require little to no cutting but the patient needs to immobilize their hand for a few weeks afterwards. Screws are a newer method of fixing broken fingers that requires little cutting and also holds the bones securely. The goal of this study is to compare the effectiveness of using pins versus screws in surgery for broken fingers. The investigators are studying whether using screws leads to better hand function, patient satisfaction, and quicker return to work.