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Fractures, Bone clinical trials

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NCT ID: NCT05748366 Recruiting - Clinical trials for Rib Fracture Multiple

Ultrasound Guided Serratus Anterior Plane Block for Rib Fractures

Start date: March 31, 2023
Phase: N/A
Study type: Interventional

This study is a single center, randomized controlled trial examining the effect of serratus anterior plane block (SAPB) on pain, PIC scores and other clinical outcomes in emergency department patients with multiple rib fractures in comparison to the use of analgesic medication alone. Objectives 1. Compare SAPB performed in the ED setting to analgesic medication alone with regard to pain, respiratory status and PIC score of patients with multiple rib fractures. 2. Assess the safety and feasibility of performing ultrasound-guided SAPB in the ED. 3. Evaluate outcomes of patients receiving the SAPB in the ED including amount of analgesic medications used, level of care required, need for upgrading level of care, and length of stay.

NCT ID: NCT05744349 Recruiting - Fracture Forearm Clinical Trials

Percutaneous Intramedullary K-wires Fixation of Pediatric Shaft Both Bone Forearm Fractures

Start date: February 28, 2023
Phase: N/A
Study type: Interventional

This study is to improving outcome of pediatric both bone forearm fractures using minimally invasive procedure by intramedullary K-wires.

NCT ID: NCT05743179 Recruiting - Pneumonia Clinical Trials

The Effect of Zoledronate on the Prevention of Pneumonia in Hip Fracture Patients

Zoo-P
Start date: December 5, 2022
Phase: Phase 4
Study type: Interventional

Nitrogen-containing bisphosphonates (N-BPs; such as alendronate and zoledronate) are commonly used in the treatment of osteoporosis and fracture prevention, in which zoledronate has a proven better efficacy than alendronate. In 2018, our real-world propensity score matched study showed that the use of N-BPs was significantly associated with reduced risk of myocardial infarction and stroke in hip fracture patients. In addition to cardiovascular diseases, both preclinical study and sensitivity analysis also suggest evidence for N-BPs in pneumonia prevention. Moreover, a pragmatic clinical trial is developed to evaluate effect of the tested intervention in real-life routine clinical practice since traditional explanatory radomised controlled trial (RCT) may have poor generalizability due to highly selected patients and controlled environments. This study aims to evaluate if zoledronate reduces risk of pneumonia in hip fracture patients using pragmatic clinical trial approach. This is an open-label, multi-centre, pragmatic, randomised controlled trial. Patients will be recruited from 4 hospitals, namely Caritas Medical Centre, Prince of Wales Hospital, Queen Mary Hospital, and United Christian Hospital. Age, sex, body mass index, eGFR, history of fracture, chronic respiratory diseases, and other medical history, will be measured and recorded at recruitment.

NCT ID: NCT05742048 Enrolling by invitation - Trauma Clinical Trials

Diagnostic Performance of Ultrasound for Primary Survey of Traumatic Long Bone Fractures

Start date: March 1, 2023
Phase:
Study type: Observational [Patient Registry]

Long bone fractures are among the most traumatic patients seen in emergency departments. Using ultrasound to diagnose long bone fractures can reduce the risk of complications occurring During the primary and secondary survey. The diagnosis of long bone fractures is traditionally accomplished through plain radiographs taken at perpendicular angles to each other. Because of the resources required for radiographic capability, X-ray can be inaccessible in rural or remote areas, or in hospital during break time, In settings where a radiography technologist is not present on-site or in patient have conditions do for him limitations movement Using ultrasound machines to do patient examination can be performed earlier of assessment, and at the bedside, reducing diagnostic delays and time to initiation of management. Additional Advantages of Ultrasound include its simplicity, portability, repeatability, and its lack of ionizing radiation. Using ultrasound technology don't need equipment for lead protectors on health care providers, as well as the harmful effects to patients of ionizing radiation and safe to use with pregnant patients in the first and second trimester. However, this technique can be impractical because the training necessary for the use of this technology Diagnosis of long bone fractures in primary assessment can decrease risk of complications such as shock, bleeding, swelling, embolism compartment syndrome, vascular or neurological damage and patient's transposition related change shape and type of a fracture. that complications can lead to life-threatening conditions up to death specifically in geriatric and paediatric Patients

NCT ID: NCT05741892 Recruiting - Fracture Tibia Clinical Trials

3D Planned Surgery of Acute Fractures Performed With 3D Guides Printed at the Point of Care

3DFRG
Start date: April 1, 2023
Phase: N/A
Study type: Interventional

The aim of the study is to assess the accuracy of fracture reduction performed with surgical guides designed and 3D printed at the point of care in comminuted fractures of femur- and tibia-shaft.

NCT ID: NCT05739240 Not yet recruiting - Clinical trials for Distal Radius Fracture

Effects of Preoperative 3D Printing of Distal Intra-articular Radius Fractures on Quality of Fracture Reduction

3PAS
Start date: March 1, 2023
Phase: N/A
Study type: Interventional

The investigators aim to evaluate the effect of a preoperative 3D printed Model (3PAS) of distal intraarticular radius fractures on quality of fracture reduction. Surgical procedure is equal in the 3PAS and in the conventional group. To evaluate the quality of fracture reduction each patient receives a postoperative CAT-scan.

NCT ID: NCT05738785 Not yet recruiting - Osteoporosis Clinical Trials

Risk of Osteoporotic Fracture in Home Care Patients in Turkey

Start date: September 15, 2023
Phase:
Study type: Observational

This study will assess the incidence of osteoporosis and osteoporotic fracture risk of registered home health patients in the Anatolian side of Istanbul.

NCT ID: NCT05737459 Completed - Clinical trials for Cognitive Impairment

Sedation and Postoperative Cognitive Functions

Start date: May 1, 2022
Phase:
Study type: Observational [Patient Registry]

Patients over the age of 65 who underwent elective surgery for a hip fracture and were sedated during spinal anesthesia were included in the study. Patients who were given ketamine and dexmedetomidine for sedation were included in the study. The Mini Mental Status Tests of the patients measured on the first and third days of the operation in the preoperative period were determined from the hospital records and recorded.

NCT ID: NCT05736068 Recruiting - Clinical trials for Distal Radius Fracture

Is Casting of Displaced Pediatric Distal Forearm Fractures Non-inferior to Reduction in General Anesthesia?

CASTING
Start date: September 7, 2023
Phase: N/A
Study type: Interventional

Treatment of displaced distal forearm fractures (DFF) in children have traditionally been closed reduction and pin fixation, although they might heal and remodel without manipulation, with no functional impairment. No randomized controlled trials (RCTs) have been published comparing the patient-reported functional outcome after non-surgical and surgical treatment of displaced DFF in children. This is a multicentre RCT. The aim of the trial is to investigate the patient-reported functional outcome after non-surgical treatment of displaced distal forearm fractures (DFF) in children. We will include 44 children aged 4-10 years with a displaced DFF. They will be offered inclusion, if the on-duty orthopedic surgeon finds indication for surgical intervention. If the parents/guardians consent to participate, the children will be allocated equally to non-surgical treatment (intervention) or surgical treatment of surgeon's choice (comparator). We will follow the children during one year, where they will be seen after 4 weeks, 3, 6 and 12 months. The primary outcome is the between-group difference in 12 months Quick Disabilities Arm Shoulder and Hand (QuickDASH) score.

NCT ID: NCT05735561 Completed - Avascular Necrosis Clinical Trials

Proximal Humerus Fracture Dislocation Direction and Avascular Necrosis

PHF-D
Start date: February 15, 2023
Phase:
Study type: Observational

The purpose of the study is to see if there is a connection between a proximal humerus fracture dislocation direction and the likelihood of developing avascular necrosis. Utilizing a retrospective cohort from the last ten years we hope to bring consenting patients back for a single visit to have x-rays and complete patient reported outcome measures to assess for evidence of avascular necrosis.