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Fractures, Bone clinical trials

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NCT ID: NCT06054165 Not yet recruiting - Pelvic Fracture Clinical Trials

Impact of a Clinical Pathway for Pelvic Fragility Fractures

PELVIC
Start date: November 1, 2023
Phase: N/A
Study type: Interventional

Patients with pelvic fragility fractures suffer from high morbidity and mortality rates. Despite the high incidence of these injuries, there is currently no regional or nationwide treatment protocol which results in a wide variety of clinical practice. New insights in treatment strategies, such as early diagnosis and minimal invasive operative treatment of these fragile patient population, has led to the development of several clinical pathways in recent literature. The aim of this study is to implement an evidence and experience-based treatment clinical pathway to improve the outcomes in this fragile patient population that currently has multifactorial risks for poor outcome.

NCT ID: NCT06051682 Recruiting - Clinical trials for Artificial Intelligence

Optimization of the Diagnosis of Bone Fractures in Patients Treated in the Emergency Department by Using Artificial Intelligence for Reading Radiological Images in Comparison With Traditional Reading by the Emergency Doctor.

FracturIA
Start date: September 11, 2023
Phase: N/A
Study type: Interventional

As part of the management of a patient with suspected bone fractures, emergency physicians are required to make treatment decisions before obtaining the imaging reading report from the radiologist, who is generally not available only a few hours after the patient's admission, or even the following day. This situation of the emergency doctor, alone interpreting the radiological image, in a context of limited time due to the large flow of patients to be treated, leads to a significant risk of interpretation error. Unrecognized fractures represent one of the main causes of diagnostic errors in emergency departments. This comparative study consists of two cohorts of patients referred to the emergency department for suspected bone fracture. The first will be of interest to patients whose radiological images will be interpreted by the reading of the emergency doctor systematically doubled by the reading of the artificial intelligence. The other will interest a group of patients cared for by the simple reading of the emergency doctor. All of the images from both groups of patients will be re-read by the establishment's group of radiologists no later than 24 hours following the patient's treatment. A centralized review will be provided by two expert radiologists. Also, patients in both groups will be systematically recalled in the event of detection of an unknown fracture for hospitalization.

NCT ID: NCT06050668 Not yet recruiting - Muscle Atrophy Clinical Trials

Essential Amino Acid Supplementation for Femoral Fragility Fractures

Start date: February 2024
Phase: N/A
Study type: Interventional

This trial will evaluate the impact of 6 weeks of postoperative essential amino acid (EAA)-based supplementation on muscle morphology after femoral fragility fracture. This trial will assess the ability of EAA-based to increase skeletal muscle metabolic activity, reduce inflammation, and induce muscle fiber hypertrophy, as well as preserve skeletal muscle mass and physical performance up to 6 months after injury. Participants will be randomized in a 1:1 ratio to 1) standard of care (no dietary intervention) or 2) EAA-based supplementation.

NCT ID: NCT06050473 Completed - Clavicle Fracture Clinical Trials

Supraclavicular Nerve During Clavicle ORIF

Start date: November 2, 2016
Phase: N/A
Study type: Interventional

Clavicle fractures are a common orthopedic injury and make up 2.6%-5% of all fractures. Despite the benefits of operative management, post-operative chest wall paresthesia is a well-known complication among surgeons and is well described in the literature. Studies reporting on the natural history of post-operative paresthesia report an incidence of chest wall numbness anywhere from 10-80% and this is attributed to iatrogenic injury of the branches of the supraclavicular nerve that provide sensation over the clavicle, anteromedial shoulder and proximal chest. While this may seem like an easy complication to avoid, anatomic studies give insight into the complex and unpredictable branching of the supraclavicular nerve. The aim of this study was to compare the area (cm2) and change in size over time of post-operative paresthesia (includes hypesthesia and dysesthesia) following ORIF of displaced clavicle fractures between nerve-sacrificing and nerve-preserving procedures.

NCT ID: NCT06046404 Recruiting - Clinical trials for Distal Radius Fractures

Refraining From Closed Reduction of Dislocated Distal Radius Fractures in the Emergency Department

RECORDED
Start date: May 8, 2023
Phase: N/A
Study type: Interventional

The investigators test the efficacy of closed reduction in displaced distal radial fractures in the emergency department.

NCT ID: NCT06033534 Recruiting - Open Fracture Clinical Trials

Evaluation of STIMULAN Device and AI Model in Preventing Fracture Infections

Start date: November 1, 2023
Phase: N/A
Study type: Interventional

This is a prospective, single-center, double-blind randomized clinical trial aimed at evaluating the efficacy and safety of the extended-release antibiotic device, STIMULAN, in preventing infections in patients with open fractures. The study will enroll 40 patients from IRCSS San Raffaele's Emergency Department and Orthopedics and Traumatology Unit. Patients will be stratified into high-risk and low-risk infectious subgroups and randomized into either the intervention group receiving the antibiotic device or the control group receiving no device. The follow-up period will last for 5 days, with data collection at specified intervals. Standard laboratory tests will be utilized to monitor the patient's inflammatory response.

NCT ID: NCT06029374 Not yet recruiting - Boxer's Fracture Clinical Trials

Therapy of Fifth Metacarpal Neck Fractures - Comparing Functional Treatment With Reposition and Finger Splinting

BoxerFx
Start date: September 2023
Phase: N/A
Study type: Interventional

The purpose of this prospective randomized controlled clinical trial is to evaluate if functional treatment leads to a better functional outcome than a forearm cast and a finger splint in patients with fifth metacarpal neck fracture.

NCT ID: NCT06029361 Recruiting - Hip Fractures Clinical Trials

Improvement of Function After Hip Fracture in Geriatric Rehabilitation Unit Via Augmented Reality Device "SELFIT"

Start date: August 8, 2023
Phase: N/A
Study type: Interventional

Type of study: prospective interventional the purposes of the research :To examine the effect of treatment using the SELFIT system on function, walking and balance in patients after hip fractures hospitalized in the geriatric rehabilitation department. The study population: 50 participants aged 65+ who were admitted to the geriatric rehabilitation department after hip fractures, with 25 in the experimental group and 25 in the control group. The main question[s] it aims to answer are: - What is the effect of training with SELFIT system on the functional outcomes in patients after hip fractures hospitalized in the geriatric rehabilitation department. - How the training with SELFIT system will effect on satisfaction of the patients in the geriatric rehabilitation department. During 21 days, both groups will receive physical therapy for about 45 minutes. The experimental group will be allocated about 15 minutes out of the 45 minutes to practice with the help of the SELFIT system.

NCT ID: NCT06028971 Recruiting - Clinical trials for Distal Femur Fracture

Safety and Performance of the Biphasic Plate Distal Femur: A Multicenter Case Series

Start date: January 30, 2024
Phase:
Study type: Observational

The goal of this observational multicenter case series is to assess the safety and performance of the CE-marked "Biphasic Plate Distal Femur" during standard of care.

NCT ID: NCT06025981 Enrolling by invitation - Hip Fractures Clinical Trials

Clinical Study of the Effects of a SWalker II and VR for Hip Fracture Rehabilitation in the Elderly

SWalker-VR
Start date: January 10, 2023
Phase: N/A
Study type: Interventional

This project is structured in two distinct phases. The first phase deals with the recovery of the hip fracture in the acute phase up to ambulation, and the second is understood as the continuation of functional improvement of gait. In the first phase, the aim is to evaluate the effects of the use of the robotic device (SWalker) on the physical improvement of the patient. While in the second phase, the objective is to evaluate the effects of virtual reality technology combined with the use of the SWalker.Therefore, the following specific objectives are identified: - Phase I: To analyze the effects of SWalker application in patients with acute hip fracture on clinical parameters of rehabilitation. - Phase II: To study the effects of the application of the SWalker combined with immersive technology in people with impaired gait function after hip fracture.