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Fractures, Bone clinical trials

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NCT ID: NCT03466242 Not yet recruiting - Clinical trials for Distal Radius Fracture

IN Dexmedetomidine for Procedural Sedation in Pediatric Closed Reductions for Distal Forearm Fractures

Start date: May 1, 2018
Phase: Early Phase 1
Study type: Interventional

The primary objective of this study is to evaluate the sedative, and analgesic effects of intranasal (IN) Dexmedetomidine (DEX) in children presenting to a Pediatric Emergency Department (PED) who undergo conscious sedation for reduction of closed distal forearm fractures when compared to those receiving intravenous (IV) Ketamine. The secondary objective is to compare each sedation technique for safety and procedural outcomes.

NCT ID: NCT03466190 Recruiting - Clinical trials for Mandibular Fractures

Clinical Assessment of Computer-assisted PEEK Versus Conventional Titanium Plates on Mandibular Body Fractures

Start date: August 2, 2017
Phase: N/A
Study type: Interventional

Two groups of patients with mandibular body fractures indicated for Open reduction internal fixation alone or in combination with fractures elsewhere in the mandible or midface. First group will be subjected to traditional titanium internal rigid fixation. Second group will be subjected to custom made PEEK plates.

NCT ID: NCT03464578 Completed - Clinical trials for Proximal Humeral Fracture

Evidence Based Algorithm for Proximal Humerus Fractures

Start date: January 1, 2014
Phase:
Study type: Observational [Patient Registry]

Proximal humerus fractures are particularly frequent injuries and represent 6% of all fractures with an overall incidence of 63/100.000 in human. The goal is to assess our institutional evidence based algorithm for treatment of proximal humeral fractures. Objective(s): 1. Test the algorithm in terms of clinical applicability and clinical outcome 2. Compare general outcome and general complication/revision rate to the literature. Inclusion / Exclusion criteria: Inclusion: All patients with an acute proximal humeral fracture (not older than 48 hours) admitted to our institution later than 1.1.2014. Exclusion: Multilevel and pathological fractures are excluded. Terminally ill patients and those not being able, or willing to sing the informed consent. Project Centre(s): Single-centre. Statistical Considerations: Standard descriptive statistics will be performed using R-statistics program. Considering the population of 160 patients, we will be able to detect differences in proportions as low as 0.15 with power 82% and alpha = 0.05. Other methodological Considerations: Terms applicability of a treatment protocol and adhesion to protocol are not well defined for decision making in orthopaedic surgery.

NCT ID: NCT03462901 Enrolling by invitation - Clavicular Fracture Clinical Trials

Fixation of Displaced Midshaft Clavicular Fractures in Adults by Intramedullary Elastic Rod

Start date: October 30, 2016
Phase: N/A
Study type: Interventional

Clavicular fracture, constitutes 2.6% e 5% of all adult fractures, most are located in the midshaft clavicle with different degrees of displacement. Conservative methods are commonly used for midshaft clavicular fractures treatment, but with various unsatisfactory complications such as nonunion, malunion and shoulders asymmetry. The rate of malunion after conservative treatment for the midshaft clavicular fractures reached 15%, and 30% patients were unsatisfied. Recently, early midshaft clavicular fractures could greatly reduce the incidence rate of nonunion and malunion. Open reduction and plate-screw fixation was considered as the gold standard with the advantages of firm fixation and earlier postoperative mobilization, but also with disadvantages of larger incision and more organizations being exposed, presenting with many postoperative complications. Intramedullary fixation treatment for mid-clavicular fractures has been favored due to its strengths including small incision, less periosteal striping, dispersion of stress and simple to operate However, early intra-medullary implants, such as Hagie pins and Kirschner wires, have been gradually replaced due to insufficient stability. In addition, various nails such as elastic stable intramedullar

NCT ID: NCT03461237 Recruiting - Osteoporosis Clinical Trials

Chinese Second Hip Fracture Evaluation

CSHFE
Start date: May 1, 2017
Phase:
Study type: Observational

1. To Compare overall rates of second hip fractures in both genders, 2. To determine the effect of hip fracture on proximal femoral volumetric bone mineral density (vBMD), bone structure and muscle by quantitative computed tomography(QCT), 3. To evaluate the contribution of QCT-image analysis to the prediction of the second hip fracture risk. 4. To identify the differences between femoral neck fracture and trochanter fracture following hip fracture

NCT ID: NCT03460418 Completed - Humeral Fractures Clinical Trials

Treatment of Humerus Fractures by a Multiloc Nail, Through a Minimally Invasive Procedure.

Start date: April 1, 2018
Phase:
Study type: Observational

Proximal humerus fractures are more common in older people. They can be caused by a minor trauma on an osteoporotic bone. Non- or little-displaced proximal humerus fractures are treated orthopedically. When the displacement is more important, the choice of the treatment is crucial and the algorithm of treatment is in permanent evolution. The technology and design of the implants and the operative techniques of osteosynthesis and arthroplasty have evolved. Patients live longer, they lead a more active life and their expectations have changed. The goals of the treatment should be an increase in shoulder function and a decrease in treatment failure. This study analyzes the results of the treatment by intramedullary osteosynthesis using a Multiloc nail from Synthes between 2012 and June 2017. The study will compare the functional results obtained after fixation by a Multiloc nail, a Philos plate or arthroplasty.The functionality of the shoulder and the quality of life will be evaluated according to the type of treatment.

NCT ID: NCT03456271 Terminated - Clinical trials for Type 2 Diabetes Mellitus and Fragility Fractures

A Prospective Cohort Study:Forecast Fracture Risk With a Serum Marker of Type 2 Diabetes in Guangzhou Community

Start date: July 1, 2017
Phase:
Study type: Observational [Patient Registry]

The objective of this study is to find out the biochemical markers which have independent predictive value of fragility fractures risk with Type 2 diabetes in Guangzhou community and evaluate bone strength better and increase the ability of recognizing fracture risk through following-up visits the bone metabolism index like esRAGE-to-pentosidine ratio of the petients with type 2 diabetes and osteoporosis,compared with the classical fracture risk assessment instrument.

NCT ID: NCT03451916 Completed - Hip Fracture Clinical Trials

Treatment of Muscle Injury Following Arthroplasty for Hip Fracture (HF)

Start date: July 26, 2018
Phase: Phase 3
Study type: Interventional

The objectives of this study are to assess the efficacy, safety, and tolerability of PLX-PAD intramuscular administration for the treatment of muscle injury following arthroplasty for HF.

NCT ID: NCT03451305 Recruiting - Clinical trials for Osteoporosis Fracture

Postrual Reduction With Pillow in Osteoporotic Vertebral Fracture

Start date: January 23, 2018
Phase: N/A
Study type: Interventional

Vertebroplasty in the symptomatic osteoporotic vertebral fracture has become increasingly popular. However, there have been some limitations in restoring the height of the collapsed vertebrae and in preventing the leaking of cement. In the severely collapsed vertebrae of more than two thirds of their original height, vertebroplasty is regarded as a contraindication. We tried postural reduction using a soft pillow under the compressed level. This study was undertaken to investigate the effectiveness of the combination of postural reduction and vertebroplasty for re-expansion and stabilization of the osteoporotic vertebral fractures. single level vertebral compression fracture were treated with postural reduction followed by vertebroplasty. We analyzed the degree of re-expansion according to the onset duration.

NCT ID: NCT03447496 Completed - Clinical trials for Lateral Condyle Fractures,Humerus,Jakob? Classification,Reduction

Surgical Treatment for the Displaced JakobⅡ Classification Humerus Lateral Condylar Fractures in Children

JCHLCF
Start date: January 1, 2018
Phase:
Study type: Observational

Multi-center Study on Surgical Treatment for the Displaced JakobⅡ Classification Humerus Lateral Condylar Fractures in Children.