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Fractures, Bone clinical trials

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NCT ID: NCT00409799 Completed - Clinical trials for Tibia Plateau Fractures

Safety and Efficacy of I 0401 in the Treatment of Tibial Plateau Fractures Requiring Grafting

Start date: November 2006
Phase: Phase 2
Study type: Interventional

For certain tibial plateau fractures the bone is compressed due to the force acting on the tibia during the accident. The void provoked by the compression of the bone is filled with an appropriate filling material and the fracture is fixated. I 0401 is a new bone graft substitute that has shown capacities to promote bone-healing. This study will test the safety and efficacy of I 0401 in the treatment of patients with tibial plateau fractures requiring grafting.

NCT ID: NCT00408291 Completed - Fracture Clinical Trials

Evaluation of Treatment of Fractures of the Humerus With a Plate.

Start date: December 2011
Phase:
Study type: Observational

The purpose of this study is to study with the use of clinical and radiological parameters the treatment of three-part and four-part fractures with the Winsta PH osteosynthesis device (Fischer Medical).

NCT ID: NCT00390741 Completed - Hip Fracture Clinical Trials

BHS4 - Bone/Muscle Changes Following Hip Fracture in Older White Women

Hip4
Start date: October 1998
Phase: N/A
Study type: Interventional

The major goals of this study are: 1. To conduct an intervention development study to evaluate the feasibility of implementing an exercise intervention for reduction losses in bone mineral density, muscle mass, and strength, and clinically relevant aspects of functioning following a hip fracture, and to obtain preliminary tests of the effective ness of these interventions. 2. To evaluate the effect of home-based exercise intervention on bone metabolism. 3. To evaluate the effects of hip fracture on bone metabolism. 4. To evaluate the effects of exercise and hip fracture on hormonal regulators. 5. To evaluate the association between markers of bone metabolism hormone regulators, and BMD. 6. To separate out the effects of hip fracture on bone turnover from those of aging in persons with low bone mineral density.

NCT ID: NCT00389844 Completed - Hip Fracture Clinical Trials

BHS5 - Testing the Effectiveness of the Exercise Plus Program

Hip5
Start date: July 2000
Phase: N/A
Study type: Interventional

The major goals of this study are: To implement a self-efficacy based intervention to strengthen efficacy beliefs related to exercise, decrease perceived barriers to exercise, and increase exercise behavior and overall activity of older women who have sustained a hip fracture. To test the effectiveness of the Exercise Trainer component of the intervention on exercise behavior, activity, efficacy expectations, barriers to exercise, performance behaviors, overall health status, mood, pain, fear of falling, falls and fall-related injuries at 2, 6, and 12 months following fracture.

NCT ID: NCT00384852 Completed - Fractures Clinical Trials

A Study of rhBMP-2/CPM in Closed Fractures of the Humerus

Start date: January 2007
Phase: Phase 2
Study type: Interventional

The primary objective of this study is to assess whether fracture union is accelerated in subjects with humeral fractures (proximal,diaphyseal) treated with conservative therapy (standard of care) and a single dose of rhBMP-2/CPM compared to subjects who receive standard of care alone.

NCT ID: NCT00384358 Completed - Fractures Clinical Trials

Feasibility And Safety Study Of rhBMP-2/CPM For Hip Fractures

Start date: December 2006
Phase: Phase 2
Study type: Interventional

The primary objective of this study is to assess the safety of administering rhBMP-2/CPM as an adjuvant to internal fixation in subjects with fractures of the proximal femur.

NCT ID: NCT00367848 Completed - Fractures, Occult Clinical Trials

Efficacy of Ultrasound in Evaluating Occult Fractures

Start date: November 2006
Phase: N/A
Study type: Observational

The purpose of the study is to examine the efficacy and accuracy of Ultrasound in evaluating occult fractures. We want to examine it on children that suffer from suspected fractures of the foot and ankle and the results of the x-ray are either negative or inconclusive.

NCT ID: NCT00358787 Completed - Humeral Fractures Clinical Trials

Management of Displaced Supracondylar Fractures of the Humerus Using Lateral vs. Crossed K-wires

Start date: July 2008
Phase: N/A
Study type: Interventional

Completely displaced (Type III) supracondylar fractures of the humerus are treated in the operating room and are held together with pins stuck into the bone. There are two ways of inserting the pins: crossed and laterally. The crossed method is often used because it is thought to be more stable, but this method also carries a risk of hitting the ulnar nerve. It is not known which method is more stable. Our hypothesis is that loss of reduction will be equivalent between the two pinning methods.

NCT ID: NCT00343252 Completed - Back Pain Clinical Trials

Effect of Teriparatide Compared to Risedronate on Back Pain in Women With a Spine Fracture Caused by Osteoporosis

Start date: June 2006
Phase: Phase 3
Study type: Interventional

The purpose of the study is to determine if daily teriparatide reduces back pain more effectively than weekly risedronate in women with osteoporosis who have chronic back pain due to a spinal bone fracture.

NCT ID: NCT00327106 Completed - Hip Fracture Clinical Trials

Tranexamic Acid in HIp Fracture Surgery (THIF Study)

THIF
Start date: April 2005
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the efficacy of tranexamic acid in hip fracture surgery on the reduction of allogeneic red blood cell transfusion.